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As you can see from the link, statistician Mike Shackleford, who runs the Wizard of Odds website, tracked about 2,100 NFL games involving road dogs and found them to win 53.75% with a 2.57% R.O.I.
I speculated that the road dogs might win a higher % if only games where they got more than 3 points were considered
I tracked this for the entire 2019 NFL regular season - I am not including pushes - there weren't many - I think just 2
Results for road dogs who got more than 3 points:
61-41.........................59.80% winners......................14.17%........ R.O.I
anyone who wants to double check my stats or work on prior seasons can do so at covers.com - they have data going back many years
I plan to scope this out next season too
I am not associated with covers.com in any way and I do not recommend their for pay services. I only mentioned them because they are the only ones I know of who make this kind of historical data publicly available
https://wizardofodds.com/games/sports-betting/nfl/