Quote:
Originally Posted by ganstaman
The puberty blockers basically just signal to the brain to stop the release of pubertal levels of hormones. But taking exogenous hormones would do the same, which is why I don't think they would generally be used together. I believe that when testosterone is given, an additional medication is sometimes given to prevent its conversion to estrogen or with something to block some of the estrogen effects. So anyway, I believe your understanding is rather correct.
I'd just add to this that my understanding of puberty blockers is they can work in different ways. The ones that downregulate the production of hormones do so at the pituitary. In other words, the hypothalamus still signals the pituitary to produce hormones, but the blockers stop it at this juncture. Other blockers work by blocking receptors for hormones, so the hormones are still produced, but they are prevented from signalling the body.
The distinction is important as "stopping" the release of hormones suggests it may not be possible to restart it. Theoretically, once someone stops taking hormone blockers, puberty should recommence but there is little/no clinical evidence either way.
Quote:
Originally Posted by ganstaman
If someone has Strep throat, do you pump them full of antibiotics, or just give them antibiotics? If someone has high blood pressure, do you pump them full of antihypertensives, or just give them medication? So why the loaded language here?
Is it relevant that the medication was first made to treat cancer? Should we judge all medications based on the first use we find for them?
It's a fair point, however I was largely aping the loaded language used by the person I was replying to:
Quote:
Originally Posted by spaceman Bryce
Trans people often talk about how cruel it is to subject them to hormones opposite of their gender, in reality it’s the same as forcing cisgender girls to take massive amounts of male hormones/testosterone or a cisgender man being forced to take feminizing hormones and estrogen.
it is "cruel" to "subject" someone to their normal bodily functions? is it the same as "forcing" someone to take drugs they don't want to?
If you are going to criticise emotive language used by individuals in this thread, then be consistent.
As the the repurposing of cancer drugs, I have no problem here as long as they have been as rigorously tested for their re-intended purpose as for their original purpose, which puberty blockers clearly haven't.
Quote:
Originally Posted by spaceman Bryce
Hello friends. Last time I was reading this thread el razor was explaining how the vast majority of children who are referred to gender clinics are not rushed into surgery or puberty blockers but rather given help based on their needs and many aren’t even diagnosed with gender dysphoria, thus refuting many false claims about gender affirming care. I guess i need to catch up.
I suspect the majority of children referred to gender clinics receive appropriate care. However, that's not good enough. If someone has cancer, you expect them to receive the best possible care available in all instances. It's not good enough to say that 80% of patients are provided with the best available care if 20% are receiving voodoo medicine, homeopathy or any other treatment that has not been scientifically proven to benefit the patient.
Last edited by Elrazor; 12-30-2023 at 01:42 AM.