Bigger,
I'll give an example to illustrate one point. Say you raise with 6
7
and get called from the blinds. Flop comes say 3
8
Q
here you have some backdoor draws only, which are hands in the bottom of my bluff range. So yo fire a cbet and get called. I would continue to bluff if my bd draws improve, and give up if they don't. The strength of your betting range should be increasing as the hand progresses, which means some bluffs will drop out. In this case you are continuing to bluff if you pick up a flush draw or a good straight draw, but otherwise giving up.
Important note: this is good against good opponents, I'm not sure how good it is against live players, but I suspect it is at least decent since I suspect live players peel a lot with hands like over cards and gut shots that they will abandon on the turn. It's also good in that you usually have some equity when you get called.
The best thing you can do is when you are away from the table play through some scenarios with assumed villains and their ranges and characteristics and your range and find the most exploitative lines you can. My impression is that live players play back with bluffs and semi bluffs way less than they should, so you will be exploiting them a lot by folding when they do. I'd recommend applications of nl by Janda to you, too. And playing the player by miller. The latter is more of a cookbook, the former a text book.