I usually do well playing small and medium stack plo but I never do well playing deep stack plo.

Any strategies and adjustment that I should try to improve?
Thanks

play tighter oop

Money over gamble

Only play small and medium stack PLO, don't bother trying to get good at something you're bad at. You'll slowly learn enough playing in games you're profitable you can ease into it

Very much this.

And wing the rest.

Seems like im going back a few years (and ive mentioned this a lot when this comes up) - Jeff Hwangs big play stategy .... or whatever his first book is called.... is pretty much still the go to FR deep stack live PLO book. In fact nothing ive read has come close to this.

Thats the general strat for profitable play. To make even more you have to get better at the soft skills. You said "I usually do well playing small and medium stack plo but I never do well playing deep stack plo."

This implies that you aren't particularly adept at playing multiple street poker; and live this is all about feel. So get focused, work out who is doing what, why they are there, physical tells etc. This will mean you can take down more orphaned pots, value bet thinner and value call and all that jazz

With experience (and this can mean both having played for years and having played at a table for 15minutes with certain opponents) you'll start to read your opponents better.

Oh and look left. <--- most important thing