Confirmed, run out for a couple of days, get heartburn bad enough to double you over.

"I really doubt there's anything to this PPIs kidney stuff. I think the 2 issues are 1) long-term absorption of stuff that needs acid to be absorbed (iron, calcium, magnesium, etc), and 2) Increased risk of pneumonia (your stomach acid usually kills all the bacteria so when you burp stuff up and it gets in your lungs you don't get sick)."

Yeah, I actually took the trouble to read the full paper instead of the abstract, along with the comments since I've been on prilosec forever. I think the jury is still out on the renal stuff - the original study wasn't really well designed at all IMHO in terms of controlling for confounding variables. The original guys said they're going to repeat the study and look more closely at it - but I dunno if or when that's going to happen. There was some handwaving about Magnesium absorption (Lack of) causing the renal issue, but I'm not enough of a kidney maven to know if it's a real worry. The pneumonia stuff I'm much less worried about - the cohort was all nursing home patients who are debilitated and at risk for aspiration anyway. I'm gonna happily ignore that.

MM MD

If you can completely avoid alcohol that helps a whole lot. And cut down on coffee if you're into that.

I have the same as Hobbes. I have been on Prevacid starting with the 30mg rx for about 20yrs. Now take the 15mg OTC pills and they control it fine.

I heard about the studies and tried to quit the pills but quickly found out about acid rebound. The rebound is a total nightmare. I can't even miss one day without complete agony.

On the other hand, taking the pills and not having the GERD ever is pretty sweet!

I would try the other suggestions first and see a Dr first before taking the pump meds.

black coffee does not create indigestion or heartburn, black coffee is medicine.

The biggest culprit is honestly probably vegetable oil. It is the hidden killer in so many foods and it is used to cook foods as well if you eat at restaurants or do takeout.

From Deep Nutrition: Why Our Genes Need Traditional Food(an eye-opener, I suggest everyone read it and start being strict with what they ingest(I know it's hard, I could do way better)):The stomach releases acid and gently massages it through the food, helping propel it through the digestive tract. The acid aids digestion by activating enzymes and killing off pathogenic bacteria, ultimately enabling us to extract as much nutrition as possible from our diets. In the presence of vegetable oils, stomach acid interacts with otherwise beneficial compounds in our food in such a way as to incite oxidative reactions that lead to the formation of MegaTrans fats that cause damage to the stomach lining (trans fats are terrible, MegaTrans fats are trans fats that literally compound inside of you).

more from Deep Nutrition: Inflammation in the gut causes heartburn, which is just the tip of the iceberg(there is another 28 feet of the digestive tract to go) and should serve as a warning that whatever you are eating is harmful. Many people, unfortunately, attribute heartburn to spices in spicy food and simply ignore the warning signs. Others quiet the gastric flames with heartburn meds and antacids, but these do nothing to block the damaging effects of MegaTrans fats ("killers," my word) on the gut.

from the book: what you can take away from this is that if you have heartburn, gastritis or other digestive symptoms, one of the simplest things you can do as a first proactive step is to eliminate veggie oil in your diet.

She then goes on to say that veggie oils may not be the only reason for the burn/indigestion but it is absolutely the best step(eliminating them from your diet) to take in fixing the problem.

What makes an oil bad? to summarize what I have learned it is the ones with compounds bonds, the more bonds, the easier they can damage with heat, something like that. Poly(more than one), polyunsaturated fats are one of the worst, it's all science.

I can't find the list of good/bad oils at the moment from the book but these are things you do not want in your ingredient list: safflower oil, cottonseed oil, corn oil, peanut oil, bleached/deodorized are bad words, the list goes on and is actually scary because almost anything in a box is going to have some of the stuff.

good oils: coconut, palm, olive, maybe some others (these do not have the compound that turns bad when heated as do the others) I tried to summarize as best I could

Also, from Twitter last night: Just met a heart surgeon at my gym, so naturally, I asked him a few questions: What do you think of veggie oils? "Stay away from them. Free radicals, inflammation, unstable, bad news, etc."

conclusion: vegetable oils may actually be worse for our brain than our gut/digestive tract, vegetable oils are terrible, stay away!

Of course it is.

Science confirms it. Avoid safflower oil at all cost! https://www.sciencedirect.com/scienc...24224417301607

Edited in case anyone doesn’t have time to get that woke about bad oils.

P2 you are living in the shadow of great poster uradoodooface. Did one of you losers ban him?

just relaying the information in the book fellas

time for some squats and stuff

Take charge of your diet. Make all of your own meals for at least a month. No restaurants of any kind. Make your own sandwiches, cook your own burgers. Avoid frozen dinners if you can. I never had a lot of heartburn issues, but when I started doing this all indigestion stopped. Nowadays I will do a meal out maybe once a week or so with no problems.

I used to get acid reflux/indigestion somewhat regularly and hardly get it anymore and I'm not entirely sure why, but I recommend not eating too late and not eating too much. There were a couple things (green pepper and broccoli) which seemed to bother me and I didn't eat for a long time, but they don't bother me anymore.

Calling thremp to explain how you're all stupid and don't know how to read science.

There are so many differing opinions and studies done on food it's really hard, annoying and slightly stressful to keep up. I didn't think peanut oil was a trans fat and it has a high smoking point so is suitable for a lot of Asian style cooking. I am not giving up peanut or sesame oil

I hope you’re not actually bothering to read the drivel p2 posts. He might be right about something, but it would only be in the infinite monkeys with infinite typewriters sense.

I skim read it and decided to ignore the advice given. Each to their own though, I'm no expert on nutrition.

grunching,

I've been on omeprazole for many years. That recent study scared me. I tried laying off for a bit, but I just can't do it. Cheapest place to get it: ebay. ships from India. I just ordered 600 capsules for $30 (up from $16 for 600 last time I ordered).

My gf is a nurse. She says the pump inhibitors tend to leach calcium from the bones, making a break the biggest risk of taking them long-term.

Great price on ebay. Even the store brands aren't cheap. I'd be a little concerned about the quality control from India but damn, what a price.