Quote:
Originally Posted by Shuffle
NoSoup, your read may turn out to be correct, but I strongly disagree and here's where I'm coming from:
RNA vaccines have never been successful before. Prior to the recent Pfizer and Moderna news, many people in that line of work believed their efficacy to be exactly zero.
I don't know what the source of your chart is, so I can't speak to it and I'm not a subject matter expert by any means. But your assertion that many people believed mRNA vaccines to be without promise is simply untrue. Astro Zeneca gave Moderna $240 million for mRNA drug rights (mRNA drugs are way, way more risky than mRNA vaccines, because the downside of mRNA is that it provokes an immune response). Pfizer invested in the mRNA vaccine without taking free money from the government that would protect them against losses if the vaccine failed -- a very strong indicator that they were confident it was likely to work.
Statnews has a good
summary of the history of the field. People were very skeptical of mRNA in the 80s and 90s, but the scientific consensus has been that the technology holds significant promise for a decade or so now.
For a more detailed science-based look at what the field thought of mRNA vaccines, I'd suggest reading
mRNA Vaccines: A New Era in Vaccinology from the Nature Reviews Drug Discovery in 2018.
Where we agree is that the executives at Moderna are sleazeballs, who have puffed the technology, raised billions and became enormously wealthy way before this vaccine and have shown no inclination to stop squeezing every dollar out of the game that they can. It doesn't follow that the technology is some kind of Theranos style shell game.
Last edited by NoSoup4U; 11-17-2020 at 02:29 PM.
Reason: Correct quote tag