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03-16-2021 , 12:35 AM
How long did it take Humans to figure out smoking is harmful?

How long did it take Humans to discover that eating in excess causes diabetes?

How long did it take Humans to discover that sugar is more dangerous than fat?

Doctors/Scientists/etc are the most arrogant people on this planet by far.

Imagine Doctors were scrutinized as much as Police lol we would be living in a much different world. They cause over 100k deaths per year from malpractice alone yet we chastise the police officers for killing a few 100 unarmed people. Legit crazy world and then we have clowns who put all their faith in their work.

Quote:
65,000 to 200,000 The minimum annual number of deaths due to medical accidents, according to
hospital records. For comparison: The annual total of all other causes of accidental death is 98,000, of
which 46,000 are from auto crashes and 11,000 are from workplace accidents.
have faith friends
03-16-2021 , 11:12 AM
Quote:
Originally Posted by jsb235
We have been injecting humans with mrna doses since 2009. The technology has been closely scrutinized through dozens of trials. The scenario you are describing is one that, if it was a concern, would have most likely been conclusively identified by now.

Targeting is obviously one of the more difficult problems with these drugs, and it's the primary reason we have mrna based vaccines and not treatments. But the side effects related to targeting and the delivery system, as far as I know, are all short-term.

If there were long-term complications, I think that would have been widely discussed during the run up to Moderna's IPO, especially since there was pretty frank discussions about all of their other issues.
I think you and NC82 are basically saying the same thing.

One of the bad things I think has creeped into science, sadly due to its politicization, is that any raising of outstanding questions is often associated with being a 'denier'. Any skepticism is labeled being a 'denier'.

NC82 did not even raise skepticism, imo, and just point to the fact that some question may be answered in such a wide scale roll out that may not have been answered prior. He never tried to peg 'likelihood'.

But even skepticism needs to be tolerated. Demonizing skeptics as soon as a preponderance of evidence reaches or nears some form of consensus and trying to cancel or shame them is so counter productive. Science grows when skeptics test their alternative theories and fail. It lends support to the growing consensus.

And yes even a consensus should be tested, from time to time even the 'remote chance' competing theories.

When you exclude everything within the realm of the possible, no matter how remote you make the consensus theory stronger.
03-16-2021 , 04:13 PM
This here is pretty bad news at first sight: https://www.sciencedirect.com/scienc...92867421002981

I haven't read it completely through, but as far as I understand this shows that some variants including the "South-African variant" evades the antibody mediated neutralization of vaccinees. Immunity response is broader than only antibodies but still, this is not good. Also a very top notch journal btw
03-16-2021 , 04:37 PM
Quote:
Originally Posted by somigosaden
What evidence do you have that there's uncontrolled production of the spike protein and that such production is causing damage to cells? The mRNA deteriorates in a matter of hours. We've vaccinated tens of millions of people, and hundreds of thousands of those were vaccinated six months ago. If there is a significant number who develop an auto-immune disorder or suffer extensive cellular damage, we'd see it by now. So unless you can show me any legit evidence...
QFT
03-16-2021 , 05:42 PM
Quote:
Originally Posted by jsb235
We have been injecting humans with mrna doses since 2009. The technology has been closely scrutinized through dozens of trials. The scenario you are describing is one that, if it was a concern, would have most likely been conclusively identified by now.

Targeting is obviously one of the more difficult problems with these drugs, and it's the primary reason we have mrna based vaccines and not treatments. But the side effects related to targeting and the delivery system, as far as I know, are all short-term.

If there were long-term complications, I think that would have been widely discussed during the run up to Moderna's IPO, especially since there was pretty frank discussions about all of their other issues.
jsb, I ask this as I do not know the answer.

Have kids as young as 6months old been getting mrna doses and if so is to the point where you think the science is basically settled and there is nothing really to learn there about potential side effects in a still forming system?

I am asking as that is the target age to eventually get to once we approach full population vaccinations.
03-16-2021 , 07:47 PM
Quote:
Originally Posted by Cuepee
One of the bad things I think has creeped into science, sadly due to its politicization, is that any raising of outstanding questions is often associated with being a 'denier'. Any skepticism is labeled being a 'denier'.
exactly and people act like we don't have past data on new medicine/technology

it's always better to be skeptical than the opposite

The problem stems from the fact that modern people think the change in lifespan is due to modern medicine rather than plumbing

Medicine is extremely overrated in how much benefit it has proved to human longevity
03-16-2021 , 08:00 PM
Quote:
Originally Posted by Cuepee
jsb, I ask this as I do not know the answer.

Have kids as young as 6months old been getting mrna doses and if so is to the point where you think the science is basically settled and there is nothing really to learn there about potential side effects in a still forming system?

I am asking as that is the target age to eventually get to once we approach full population vaccinations.
I wouldn't give any covid vaccine to anyone that young as the virus doesn't really have any impact on that age group.

As far as the safety profile of mrna treatments in general, we are going to have a lot of info about them in the next few years that we didn't have before. So we will have a much better handle on side effects of the existing tech.

The next big step in the field is transitioning from vaccines to treatments, which will require a pretty big leap forward. But this segment of the industry is flush with cash right now, so that seems likely that will happen. If I was going to guess, I would say that improvements in the delivery systems and the molecule designs of the drugs themselves will lead to a reduction in side effects, which will increase the number of medical conditions these drugs can be used to treat.

It's somewhat important to remember that the pot of gold at the end of the rainbow is cancer treatment. And that's when I think you would see a lot of children getting these medications. I honestly don't see the point in giving young children any mrna-based treatment right now, since there are a lot of unknowns and covid isn't dangerous to them. But obviously a potential treatment for brain cancer changes the game considerably.
03-16-2021 , 09:09 PM
49% of Republican men (vs 6% Democrat) say they won't take the vaccine. Well done, let's be anti-science and keep this pandemic rolling. Getting closer to 600k, come on 'Murica we can do it!
03-16-2021 , 10:17 PM
Quote:
Originally Posted by lvr
The problem stems from the fact that modern people think the change in lifespan is due to modern medicine rather than plumbing

Medicine is extremely overrated in how much benefit it has proved to human longevity
Horse ****. Countries with the longest average life expectancies largely do so due to modern medical science, and life saving surgical procedures and pharmaceutical treatments that add years or decades to the lives of people who would otherwise die.

03-17-2021 , 01:27 AM
Quote:
Originally Posted by despacito
Horse ****. Countries with the longest average life expectancies largely do so due to modern medical science, and life saving surgical procedures and pharmaceutical treatments that add years or decades to the lives of people who would otherwise die.
99.99% of humans that eat healthy and exercise every day will never need to see a doctor until much later in life where all you are doing is fighting against the inevitable

I have not seen a doctor nor taken any medicine for over 20 years and I'm fine lol most of that **** is pointless and doesn't help unless you have some outlier disease

You are severely overestimating how much benefit those things have done for humanity at large when compared to plumbing. If anything I would say it has made humans unhealthier since they rely on these medicines to cure things that did not curing in the first place.
03-17-2021 , 01:49 AM
Quote:
Originally Posted by lvr
99.99% of humans that eat healthy and exercise every day will never need to see a doctor until much later in life where all you are doing is fighting against the inevitable

I have not seen a doctor nor taken any medicine for over 20 years and I'm fine lol most of that **** is pointless and doesn't help unless you have some outlier disease

You are severely overestimating how much benefit those things have done for humanity at large when compared to plumbing. If anything I would say it has made humans unhealthier since they rely on these medicines to cure things that did not curing in the first place.
You clearly have a firm grasp on pathology and genetics.
03-17-2021 , 09:45 AM
Quote:
Originally Posted by jsb235
I wouldn't give any covid vaccine to anyone that young as the virus doesn't really have any impact on that age group.

As far as the safety profile of mrna treatments in general, we are going to have a lot of info about them in the next few years that we didn't have before. So we will have a much better handle on side effects of the existing tech.
...
I agree entirely.

And for the record your post (the bolded) contains skepticism. The science is not settled on health impacts, we have lots to learn from lots of new info yet to be gathered.

There are many questions that will be answered.

Now your skepticism may not necessarily include any doubt of harm. You may. as a betting man believe it is already 99.9999% proven enough that you think no real significant deleterious harmful affects will be shown and that is a fine extrapolation for you.

But that is why I would not equate NC82's post as denialism. He is not countering the prevailing science and saying it is wrong. He just says there are still questions to be answered. He may peg the risk differently than you but he certainly was not fear mongering.

And to me point, I see a real troubling trend if such 'skepticism' is labeled immediately with the 'denier' label. It can prevent or demonize legitimate issues being explored, and even outlier positions can and should be tested and included or excluded in science.
03-17-2021 , 06:51 PM
They are also now talking about "Passive Immunity".

They are finding now women who had the vaccine at some point during a known or not yet known pregnancy are passing off some immunity to the child who is born.

So they are suggesting that vaccinating her later in the pregnancy may be better in terms of improving that immunity.

Now while I don't necessarily think any thing wrong will come from this, we should admit this is an experiment in real time. It could potentially take decades to see some negative side effects.
03-18-2021 , 10:01 AM
Thought this was pretty interesting:

Norwegian experts say deadly blood clots were caused by the AstraZeneca covid vaccine
Quote:
“The reason for the condition of our patients has been found”, chief physician and professor Pål Andre Holme announced to Norwegian national newspaper VG today.

He has lead the work to find out why three health workers under the age of 50 were hospitalized with serious blood clots and low levels of blood platelets after having taken the AstraZeneca Covid vaccine. One of the health workers died on Monday.

The experts have worked on a theory that it was in fact the vaccine which triggered and unexpected and powerful immune response - a theory they now believe they have confirmed.

“Our theory that this is a powerful immune response which most likely was caused by the vaccine has been found. In collaboration with experts in the field from the University Hospital of North Norway HF, we have found specific antibodies against blood platelets that can cause these reactions, and which we know from other fields of medicine, but then with medical drugs as the cause of the reaction”, the chief physician explains to VG.
"Nothing but the vaccine can explain why"

When asked to clarify why he says “most likely” in the quote, Holme confidently responds that the reason for these rare cases of blood clots has been found.

“We have the reason. Nothing but the vaccine can explain why these individuals had this immune response”, he states.

VG also asks how Holme can know that the immune response is not caused by something other than the vaccine.

“There is nothing in the patient history of these individuals that can give such a powerful immune response. I am confident that the antibodies that we have found are the cause, and I see no other explanation than it being the vaccine which triggers it”, he responds.
Doesn't bode well for future autoimmune disorders either imo
03-18-2021 , 02:06 PM
spirited debate

03-18-2021 , 02:15 PM
Rand Paul is an idiot
03-18-2021 , 02:46 PM
thanks for sharing

insightful
03-18-2021 , 03:35 PM
Quote:
Originally Posted by juan valdez
spirited debate



Rand Paul doesn't understand variants. The Brazil strain has reinfected thousands who already had the original wild strain. It's obvious that recommending masks when out in public, even to those who were infected or vaccinated, is simply a precaution until we reach herd immunity and the virus is no longer widely circulating. Which, given anti-vaxx Republicans and their distrust of science, might never happen in the US.

The obsession right wingers have with masks is hilarious. It's ok Rand you won't look like a sissy I promise.
03-18-2021 , 04:33 PM
Quote:
Originally Posted by revots33
Rand Paul doesn't understand variants. The Brazil strain has reinfected thousands who already had the original wild strain.
I can't find the link, but apparently the original study of Brazil's infection rates that were used to disprove the notion of herd immunity were deeply flawed or misinterpreted. Additionally, there is a pretty big political battle going on where critics of the current president are using his covid response to attack him.

Basically, I think it would be a bad idea to use Brazil as an example of anything right now.

Edit: Found the discussion on the Brazil study issues.

https://twitter.com/sailorrooscout/s...42419188350976

Last edited by jsb235; 03-18-2021 at 04:51 PM.
03-18-2021 , 09:06 PM
Quote:
Originally Posted by revots33
Rand Paul doesn't understand variants. The Brazil strain has reinfected thousands who already had the original wild strain. It's obvious that recommending masks when out in public, even to those who were infected or vaccinated, is simply a precaution until we reach herd immunity and the virus is no longer widely circulating. Which, given anti-vaxx Republicans and their distrust of science, might never happen in the US.

The obsession right wingers have with masks is hilarious. It's ok Rand you won't look like a sissy I promise.
just stop man

you're like a broken record

first there was asymptomatic people getting permanent lung damage lol

then there was getting covid twice lol

now there is getting covid more than once from different strains

just stop this bs people like you who live perpetual angst always die early

it's not good for your body
03-18-2021 , 09:07 PM
it's also ****ing hilarious now that people want to get the vaccine then also want to continue wearing double masks

like what the **** is going on...
03-18-2021 , 09:17 PM
Fauci is the best lol

Guess we will be double masking forever now

Might as well triple mask just in case new virus' pop up in the future that can bypass two

Always fear the unknown
03-18-2021 , 10:31 PM
Quote:
The EU's leading states are to restart their roll-out of the Oxford-AstraZeneca Covid-19 vaccine after Europe's medicines regulator concluded it was "safe and effective".

The European Medicines Agency (EMA) reviewed the jab after 13 EU states suspended use of the vaccine over fears of a link to blood clots.

It found the jab was "not associated" with a higher risk of clots.

Germany, France, Italy and Spain said they would resume using the jab.

It is up to individual EU states to decide whether and when to re-start vaccinations using the AstraZeneca vaccine. Sweden said it needed a "few days" to decide.
The whole episode has been somewhat tragic imo but the 'big' countries are resuming use of the vaccine and the rest will no doubt follow. fwiw the EMA who had always said the AZ vaccine should be used, now say it should be used!

Is there a genuine issue? Well maybe (I'd even say probably) but what doesn't and it's so small compared to the side effect of sitting on their arses.
03-19-2021 , 03:14 AM
Quote:
Originally Posted by lvr
Fauci is the best lol

Guess we will be double masking forever now

Might as well triple mask just in case new virus' pop up in the future that can bypass two

Always fear the unknown
Considering the indication we got on this virus at an early stage, I'm personally more than happy to be careful until more data is presented.

An ongoing study, where 300 people are being monitored closely, 60% of them are suffering long terms effects of corona. And this is 300 people who were not hospitalized in the agerange 16-30 years. 10-15% have consentration and memeory issues, while others are suffering of fatigue/tiredness, difficulties breathing and loss of smell/taste.

I would like to stay active for the last 40-60 years of my life, so I will definitelly not risk that ****. And if I have to live a bit differently for a year or two more, then that is fine by me.

The damage we saw to tissue early on, was a nobrainer warningsign that this was not something to mess around with. Death is one thing, to low chance to make me worry, but reduced lifequality for the rest of my life? No thanks.
03-19-2021 , 01:38 PM
Quote:
Originally Posted by revots33
Rand Paul doesn't understand variants. The Brazil strain has reinfected thousands who already had the original wild strain. It's obvious that recommending masks when out in public, even to those who were infected or vaccinated, is simply a precaution until we reach herd immunity and the virus is no longer widely circulating. Which, given anti-vaxx Republicans and their distrust of science, might never happen in the US.

The obsession right wingers have with masks is hilarious. It's ok Rand you won't look like a sissy I promise.
I understand what Fauci is saying, its if its valid or hypocritical that is catching peoples attention. Is this analysis on the Brazil risk valid? Overstated? Understated? We've gone from you can wear a mask if you like but it's pretty much useless to wearing 2 masks is a good idea and once you get vaccinated you should continue to wear a mask. Those mixed signals are coming from the head expert. Is wearing a mask while vaccinated the only measure that's going to be taken to protect us moving forward?

When you get in to the idea of wearing masks for variants ect, where do we draw the line? There's an annual flu shot. Every year there's a flu strain we try to minimize. Wouldn't masking up help that effort also? Are masks the only thing/restriction?

We've beaten the numbers to death but people in the lower risk age groups want to have their lives back. They don't want restrictions decimating them financially and they don't want their quality of life attacked either. People are not happy with an isolated and masked existence. If being vaccinated isn't going to change that, they start to wonder how far this is going to be taken. It's been a year of 2 weeks to flatten the curve.

      
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