Game is 5/10 Live. Sb has about $500, Hero has 2k, MP has me covered. Sb is a tight middle aged woman who alomost never makes moves, MP is a huge station who severely overvalues hands. UTG+1 limps, MP limps, I limp along in CO with QJo, Sb calls BB checks. Flop is QdJc9d. Sb bets 50, UTG+1 and MP both call and I raise to 250. Sb moves all in for $500, UTG+1 folds, MP calls. I'm 80% sure Sb has me beat, but MP can have any FD, pair+open ender, any two pair, mayber KQ or AQ or a straight. What should I do?

I dont like just calling cuz theres so many ****ty turn cards to come that will make u fold to a bet and you just wasted $500. 8 10 k A any diamond so I either 4 bet and make it 1k or fold. Do you really put the SB on K10? or 810 or 9's? You said shes super tight if she flopped a straight dont u think she wants to check raise and not just bet out? She probably has A pair and a draw or Q9 J9 or J10 Q10 or maybe QJ. I think you should 4 bet the MP's flat call seems a bit odd. Im a live player and from experience when a really loose player just calls multi way hes not that strong. So i just make it 1k straight

raise since you're sure mp will come along with weaker hands, fold if you doubt that, never flat call.

agreed