**8*8*8 March version Two(2) ***88***8 - Page 28

DNP acts as a protonophore, allowing protons to leak across the inner mitochondrial membrane and thus bypass ATP synthase. This makes ATP energy production less efficient. In effect, part of the energy that is normally produced from cellular respiration is wasted as heat. The inefficiency is proportional to the dose of DNP that's taken. As the dose increases and energy production is made more inefficient, metabolic rate increases (and more fat is burned) in order to compensate for the inefficiency and meet energy demands. DNP is probably the best known agent for uncoupling oxidative phosphorylation. The production or "phosphorylation" of ATP by ATP synthase gets disconnected or "uncoupled" from oxidation.

Sounds good, right? So what's the catch?

Quote:

Interestingly, the factor that limits ever-increasing doses of DNP is not a lack of ATP energy production, but rather an excessive rise in body temperature due to the heat produced during uncoupling. Accordingly, DNP overdose will cause fatal hyperthermia.

Ah... right.

The first line of DNP's wikipedia entry is also pretty clear-cut:

Quote:

2,4-Dinitrophenol (DNP), C6H4N2O5, is a cellular metabolic poison.

Science is so cool.

03-08-2010 , 07:39 PM

#678

anononon

Guest

Posts: n/a

Hrm. Now that I'm flooding this thread with stuff no one cares about, has anyone heard anything about this?

http://www.flexcart.com/members/elit...d=182&pid=3362

03-08-2010 , 07:43 PM

#679

Claunchy

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Quote:

Originally Posted by TomCollins

Tons of people drink chocolate milk on SS.

I know a lot of people drink chocolate milk PWO (I certainly do) but I'm not aware of anyone who did a GOMAD (or half or whatever) with chocolate milk. Seems like a bad idea because the macros aren't nearly as good. Most chocolate milk is low fat and very high carb.

03-08-2010 , 08:08 PM

#680

Bone Machine

centurion

Join Date: Feb 2009 Posts: 165

I could swear I made some 2,4-DNP for some reason during my undergrad chemistry work. Definitely some assorted nitro-plus-other-stuff-phenols. They did tend to have very distinctive, pleasant smells. Wish I knew at the time I could have gotten shredded if I started snorting it. DNP + ice baths = sickest weight loss protocol ever?

03-08-2010 , 08:11 PM

#681

anononon

Guest

Posts: n/a

Quote:

Originally Posted by Bone Machine

DNP + ice enemas = sickest weight loss protocol ever?

FYP

(And yes, that actually happens to people who OD on DNP.)

03-08-2010 , 08:56 PM

#682

<3_Tha_Grind

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Quote:

Originally Posted by kyleb

Hrm. Now that I'm flooding this thread with stuff no one cares about, has anyone heard anything about this?

http://www.flexcart.com/members/elit...d=182&pid=3362

I just saw it today, seems interesting although I don't play football. I may buy it just for ****s and giggles.

Did you read the interview on EliteFTS?

03-08-2010 , 10:44 PM

#683

AZK

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Quote:

Originally Posted by Bone Machine

yeah you used it in orgo 2, to confirm end products i think?

i miss chemistry.

03-08-2010 , 11:05 PM

#684

Bone Machine

centurion

Join Date: Feb 2009 Posts: 165

Quote:

Originally Posted by AZK

yeah you used it in orgo 2, to confirm end products i think?

i miss chemistry.

Haha, no, just as an intermediate for a project that went down in flames soon afterward.

I imagine you're talking about, like, making a DNP-yl ester to get a good melting point?

Last edited by Bone Machine; 03-08-2010 at 11:11 PM. Reason: next time i'll use google instead of making stupid guesses

03-08-2010 , 11:11 PM

#685

AZK

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eh, maybe. it's been 7 years since i've opened a chem book.... would love to get back into it, have no idea how likely/possible that is...

03-08-2010 , 11:49 PM

#686

Thremp

banned

Join Date: Nov 2005 Posts: 36,452

Easy way to make up for a 400 caloric overeat... get a stomach ache and fall 1150 calories short :/

03-09-2010 , 02:08 AM

#687

nation

Indian Nightmare

Join Date: Dec 2005 Posts: 8,584

lol time for a hungover lift session. my finances are in shambles due to way too much bottle service. i feel so gross right now.

03-09-2010 , 02:13 AM

#688

theblackkeys

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Quote:

Originally Posted by cookie

gtg protocol for chinups?

you grease the groove. Do them over and over and over while fresh. Avoid failure, but use a fairly high daily volume.

03-09-2010 , 03:05 AM

#689

milesdyson

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lyle questioned zach's depth in the zach thread on his forums. asked if anyone had video proof he was reaching parallel. cool little drama imo.

03-09-2010 , 03:09 AM

#690

kidcolin

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link?

03-09-2010 , 03:11 AM

#691

milesdyson

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http://forums.lylemcdonald.com/showt...?t=6654&page=9

Quote:

Originally Posted by lylemcd

I call this the Weider Add Weight and Cut Depth Principle. Usually you see it in an acute workout. Taht beuatiful deep 135 squat becomes a quarter knee bend by the time 315 gets on the bar

Happens over a series of workouts as well and, as noted, anybody who went from 145 to 345 in 3 months did not do it by maintaining depth or form. I look forwards to be proven wrong if I am though.

best post imo. i really would have questioned the assertion if not for what we've seen at 70sbig. still i have to think there's only a small chance he's actually very shallow. but if nothing comes out, it makes it really quite epic, because a dude who is willing to have those pictures posted should be more than happy to videotape a workout to prove someone wrong.

03-09-2010 , 03:14 AM

#692

kidcolin

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i didn't realize lyle posted on Rip's board. guessing lylemd. lol me.

03-09-2010 , 03:48 AM

#693

wannabecardiotard

banned

Join Date: Feb 2010 Posts: 219

oh man i love me some internet drama.

http://startingstrength.com/resource...ad.php?t=15302

Quote:

Originally Posted by lyle mcdonald

Seriously, are you guys all just illiterate morons?

I didn't say anything about Mark Rippetoe himself. In fact I said repeatedly that I have nothing but good things to say about him and his books, despite a few minor disagreements, etc. Anybody who doesn't believe me can join the island and read the thread to see how much of a lying dip**** the guy who started this thread is.

My comments were about you idiots and the stupidity of YOUR postings on this forum. Like this thread for example. So thank you for proving my point about this forum and how you're all a bunch of illiterate dickswingers who think that reading Starting Strength means you know jack ****ing **** about everything.

Lyle

i get a pretty nice thremp vibe from this lyle guy. or maybe its the other way around.

03-09-2010 , 03:56 AM

#694

kidcolin

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pretty sure thremp has bowed down before lyle's trolling abilities before.

03-09-2010 , 04:06 AM

#695

skunkworks

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Can anyone think of any plausible scenario where one could squat past parallel but couldn't deadlift more than that?

03-09-2010 , 04:13 AM

#696

wannabecardiotard

banned

Join Date: Feb 2010 Posts: 219

squat goes up 15 lbs a week. dl goes up 5. mebbe he just has a lot of dl gains left and hasnt been pushing it hard. coulda got kinda stuck on dl early and slowed up and then didnt accelerate to potential.

03-09-2010 , 05:06 AM

#697

Micturition Man

Pooh-Bah

Join Date: Nov 2003 Posts: 5,159

Quote:

Originally Posted by skunkworks

Can anyone think of any plausible scenario where one could squat past parallel but couldn't deadlift more than that?

The DL/squat discrepancy is super striking and there has to be an explanation for it. I thought Justin had commented on Zach having DL form problems and having to reset, I dunno I could be misremembering.

And of course there could be some 70sbig depth shenanigans going on. But Zach would have to be seriously cheating on depth for that to completely explain the DL/squat discrepancy.

I still don't see how any of this does much to repair the hole that Zach's progress seems to blow into Lyle's ~2 pounds/mo argument.

03-09-2010 , 05:12 AM

#698

Soulman

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A form problem/reset could easily explain the discrepancy. See: my/dero's log.

03-09-2010 , 05:16 AM

#699

Evoken

2014 Golden Loco

Join Date: Oct 2007 Posts: 10,302

I just found out what 21s for teh gunz are and I want to puke all over somebody who does them in the squat rack next time I see it.

03-09-2010 , 05:22 AM

#700

milesdyson

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mic man,

you really need to thoroughly read all the threads. lyle never once said the limit on anyone like this would be 2lb per month. the article itself, obv written long before this debacle, even claims that this is not a hard limit and that it can be further surpassed by someone starting as thin/young as zach. what he has said recently is that rip is grossly overestimating the actual lbm gain. he has said that 10lb of this "muscle gain" could be attributed to increased glycogen. the worst part of this whole thing is people continually claiming the argument is 2lb/month vs. 7 or whatever rip is saying zach gained.

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