Dem,
Excellent post for getting recs, very easy to answer posts like this.
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Originally Posted by Demiurge
Best craft beer bars? I'm familiar with Mikkeller Bar and will definitely be going there.
Mikkeller for sure.
City Beer Store (they are not far from Mikkeller, and also right around the block from amazing brewery, Cellarmaker).
Toronado and Zeitgeist (with great outdoor patio) are awesome divey beer bars.
Monk's Kettle is good, especially if you're into belgians.
Shotwells another really good one.
There are many others, though, and also lots of bars that are not specifically beer bars have excellent draft and bottle selections.
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Best local/regional breweries I should look out for? I've heard a lot about Modern Times and will be looking for their stuff.
I wouldn't worry too much about looking out for specific breweries at bars, every bar and restaurant you go to will have tons of excellent west coast stuff. Modern Times is one of my favorites, but there are just tons more. Check the Beer thread for much more discussion on this.
Breweries/brewpubs that are great to visit:
Cellarmaker
Rare Barrel - this is a sour beer brewery in Berkeley, amazing if you like sour beer
Fieldwork - also in Berkeley, one of my favorites
(above are mainly breweries)
Some good more mainstream brewpubs:
21st Amendment
Magnolia (two locations, Smokestack BBQ restaurant is the flagship)
Drake's Dealership
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Arcade/game/bowling place?
No idea, not sure if SF is the best place for that kind of stuff. I mean, there are bowling alleys and stuff, but it's not a big thing.
Mr. Tipples Recording Studio is a new bar w/ live jazz that I love, but it's more of a bar w/ live jazz players rather than a jazz place.
SF is not a great jazz city, most of the live jazz focused places have closed in the last few years. You'll find a few in the Fillmore and North Beach neighborhoods.
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Best charcuterie and cheese spot?
Tons and tons of bars/restaurants will have great cheese/charcuterie plates. Some of my favorites:
Mission Cheese (great cheese, charcuterie, wine)
Trou Normand (amazing charcuterie made in-house, great cocktails)
Boccalone, Fatted Calf (great places to buy charcuterie for lunch/picnic/etc)
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Best way to get out to Napa for half a day? Best way to experience it? Is it worth it in general? I don't want to be bored after a couple hours and regret the trip out there.
It doesn't really make sense to do for half a day. You'd rent a car, drive out there for 60-90 mins, go to a winery or two, then drive back 60-90 mins. The easiest way to do some wine tasting is one of these tours:
http://www.winecountrytourshuttle.com/ They are something like $100 + some minimal add'l tasting fees, pick you up at 8am for a bus ride there, then bring you back on a ferry arriving back about 5. The wineries they visit are nothing special, but totally fine/good for people who aren't super wine snobs. Very convenient from where you're staying. Wine tasting is really the only reason to visit Napa, so just decide if that's something you're into enough to want to spend a day of your trip on that.