I chose axe and dual swords. Mostly use the axe still, tho I have tried spear and single sword at various times (usually when stuck).
Beat Batlady last night with Axe, was at least 20 tries of not more like 30 but in the end got it with no buffs used and elixirs to spare
Tried every weapon on her trying to find something OP, in the end nothing worked and had to master dodging. Dropped my weight load to 29% which I think helped, reckon that allowed me to use high stance axe with a similar dodge speed to medium load low stance.
edit: IFX - yes diablo-ish random loot, and yes when you die you lose your souls (and spirit animal) and need to go collect them. Die again and the souls are gone forever, the spirit animal returns with his super meter empty (he was guarding them). Die when you don't have your spirit animal and any souls you were carrying are instantly lost.