Hi guys,
I have come across this problem many times during my last couple of sessions. I open EP/MP and random/unknown player 3bets my 2,5bb oR to 10bb.

Sorry I could not upload pictures
the links are harmless


I play a strategy which is based on avoiding playing 3bet pots OOP with no iniciative, so I tend to 4bet a lot OOP and call only small amounts.

Here are two examples of ranges I use (CALL/FOLD)

EP vs MP 3b range:
https://imgur.com/a/baE17R8

MP vs CO 3b range:
https://imgur.com/UU9rAlj

How do I want to adjust to the villain's bigger 4x 3bet size?

Ideas:
- I dont want to be calling much against this sizing....
- I fold most of the pairs, calling only the better one 77-99 but only sometimes
- Do I want to call AQs, AJs, KQs and 4b/fold the other hands (AQo,ATs, KJs, KTs)?

How would you guys adapt?
Any tips on population tendencies? - are these 3bet more value/bluff heavy?

what pool you play ?

I play 50nl on stars, zoom and regulars

your question is very vague. against a larger sizing we want to fold more and are rather inclined to 4b more and call less because the price we get on the call is worse.
but how wide you want to call /4b still depends on your opponent. it looks like you are using solver/equilibrium ranges. keep in mind that these ranges usually get created by facing a linear 3betting range with villain not having a flatting range. weaker players usually flat IP and 3bet more polar and too tight so you need to react to that.

That is actually really good point, their ranges are rather polar.
If we open raise 2,5bb and they 3bet to 10bb we need around 35% equity to call.
If we assume their range is mostly strong with few bluff (something like AQo+, AQs+, JJ+ AK) we can massively overfold right?. Hands like KJ KQ AJ QJ will just not realize equity OOP and are mostly dominated.

When it comes to countering this strategy with 4bets, I think it would be best to 4bet bluff against later positions like BN/CO when their 3bet ranges could be wider.
- but if we 4bet we isolate ourselves into their strong parts of range and fold out the weaker hands, thats what I dont like.

Would you consider this to be a good adjustment? - This is based on a fact that villain is unknown player.
I am kinda confused what to do in this situation. We should make some conclusion from this

Why do you want to have 35% equity ?