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E.g. if I have a flushdraw with 9 outs on the flop, and I am being offered 25% (3:1) pot odds, is that a long term winner or loser?
It depends, stack sizes, player types, the quality of your flush draw, the existence of hidden outs, the possibility of winning the hand by bluffing on future streets, there are many different factors at play here. There is a world of difference between a baby flush draw and the nut flush draw.