Some more info is emerging. It's concern about unusual symptoms rather than number of cases which is very small.

https://www.bbc.co.uk/news/world-europe-56440139
The whole episode has been somewhat tragic imo but the 'big' countries are resuming use of the vaccine and the rest will no doubt follow. fwiw the EMA who had always said the AZ vaccine should be used, now say it should be used!

Is there a genuine issue? Well maybe (I'd even say probably) but what doesn't and it's so small compared to the side effect of sitting on their arses.

Grain of salt.




"A Guide to Home-Based COVID Treatment"
https://aapsonline.org/CovidPatientTreatmentGuide.pdf


PairTheBoard

Maybe it is going on to a much greater degree than is being publicized, but it seems incredible that more scientists or top notch doctors are not concentrating on the fact that eighty year olds are at least 100 times more likely to die than forty year olds. They give general reasons but I never see precise molecular reasons that should not be too hard to find given such extreme evidence. Reasons that would likely lead to a cure or better treatments.

There doesnt seem to be anything significantly intriguing of therapeutic value derived from studying the rate differences other than the obvious. That is several essential to health recovery components highly correlated to old age in eg immune system, lung function, diabetes, obesity, asthma, co morbidity, cancer, past lifestyle choices, overall quality of recovery from adversity etc all deteriorate exponentially and cumulatively enhance probability of failure a couple of orders of magnitude. I would add that people living in care facilities get exposed to greater viral loads as secondary targets of the virus than the first person that opportunistically gets it in that system. The first has a smaller viral attack initially than the ones that are already there living exposed to the release of viral particles of the earlier targets. So if older people tend to live more together with others than younger people the chances of secondary exposure is higher too leading to worse than the original attack. You get clusters of substantial failure.

Worth going over all this next even if dated still relevant

https://news.cornell.edu/stories/202...-deadly-others

"Age is one risk factor. Compared to younger patients, middle-aged and older ones are far more likely to suffer symptoms, to be hospitalized and to die. One recent analysis of Chinese data estimated the chance of death in confirmed COVID-19 cases at more than 13% for patients 80 and older, compared to about 0.15% for patients in their 30s, and virtually 0% for patients under 20. A study of early U.S. cases by the Centers for Disease Control and Prevention (CDC) had similar findings."


"Catching a low dose from someone who was mildly symptomatic on the subway may involve a lower risk of severe illness,” Pelzman said, “compared to catching a high dose from a very sick and highly contagious patient.”

Were the 30 out of 18 million predisposed to get the unusual blot clots?

Not for the people who died, they didn't.

https://www.bbc.co.uk/news/health-56620646

US Death Clock: [From all causes - that should be obvious but wanted to state it explicitly]

https://www.indexmundi.com/clocks/in...spects%202019.

For the USA:

A person dies approximately every 11.14 seconds

Number of deaths per year: 2,830,688

Number of deaths per day: 7,755

Number of deaths per hour: 323

Link below shows Live World Death Totals from all causes (This Year and counting)

live-world-death-totals

P.S. More than 15 million people have died so far this year.......

Dont know. I suspect there's somthing real because they're not finding the same presentation as for other vaccines. But in general we have to consider that:

a) could be the data is being sqeezed too hard. Can always find very significant looking common factors/effects in small result sets.

b) the potential for the problem of the illusion of a rise in occurrences of anything you make more effort to look for or measure more accurately.

Either way, at worst it's absolutely tiny compared to the UK's 150k+ deaths (plus a huge number of severe illness) from covid so far. I suspect most of them would have preferred the benefits of the vaccines over the risk.


[And as always with these things. It's simply not a concern in the UK because we all died of BSE]

Exactly. And so it now becomes clear if 4000 are added to that number every day due to covid because leadership was and still in many places is inept, morally bankrupt and overall criminal mfers, plus 30-40% the population is a bunch of selfish punk ignorant cowards that do not care for others, then something is very wrong.

You fix this wrong by becoming scientific and ethical about it all and by telling China who the real boss will remain forever the right way until all is united properly and starts the true epic.


Do i ever expect some loser to understand why it is still important to wear a mask even after having vaccinated? Punks that ignored math at school did it for the very same reason they fail today. Because they decided laziness is ok and settling for simplistic reasoning is enough. You got to be a little less of a punk lazy sob to realize how important patience, love, empathy and personal efforts are.

https://forumserver.twoplustwo.com/3.../index143.html

“By blocking a protein called CD14 during the early stages of COVID-19 respiratory disease, the monoclonal antibody IC14 could potentially temper the immune system’s harmful inflammatory responses to SARS-CoV-2, thereby limiting associated tissue damage and improving patients’ health outcomes,” said NIAID Director Anthony S. Fauci, M.D.

https://www.nih.gov/news-events/news...disease-begins


PairTheBoard

Maybe not 100% on topic, but good science requires good data, and here is an interesting case.

"On March 1 2021, an outbreak [of an E484K variant] occurred in a Kentucky skilled nursing facility... [where] 90.4% of residents and 52.6% were staff were vaccinated."

They very carefully monitored the health of everyone, and this is what they found:

Unvaccinated Residents vs Vaccinated Residents
75.0% vs 25.4% infection rate
62.5% vs 8.5% symptomatic rate
50% vs 3% hospitalization rate
25% vs 1.4% death rate

Unvaccinated Staff vs Vaccinated Staff
29.6% vs 7.1% infection rate
27.8% vs 3.6% symptomatic rate
no hospitalization, no death in either group

https://yourlocalepidemiologist.subs...WBU0DfPZRvbLOY

Don't remind them. Kindly focus on covid deaths only and let it be the basis of most of all life's everyday decisions. Since they all think alike, perhaps comfort them for your own gain.

Forty-five minute talk by a UK Pathologist on COVID. Very worthwhile and interesting.

Suppression of Early Treatment




PairTheBoard

Dr. Patterson appears to have identified the cause of longhauler covid. Vasodilation due to inflammation of vascular walls caused by expression of the S1 (spike) protein by non-classical monocytes. He has had consistent success treating numerous patients with the combo therapy protocol of a CCR5 antagonist (maraviroc), ivermectin, and statins. Leronlimab could be used instead of maraviroc if it gets approved and becomes available.



Patterson's website for longhaulers.
https://covidlonghaulers.com/

FLCCC Alliance - Ivermectin
https://covid19criticalcare.com/


PairTheBoard

New Bruce Patterson paper about Long Covid

Quote:
--------------------
Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection

https://www.biorxiv.org/content/10.1...06.25.449905v1

The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected individuals. The underlying mechanism and source of this distinct immunologic condition three months or more after initial infection remains elusive. Here, we investigated the presence of SARS-CoV-2 S1 protein in 46 individuals. We analyzed T-cell, B-cell, and monocytic subsets in both severe COVID-19 patients and in patients with post-acute sequelae of COVID-19 (PASC). The levels of both intermediate (CD14+, CD16+) and non-classical monocyte (CD14Lo, CD16+) were significantly elevated in PASC patients up to 15 months post-acute infection compared to healthy controls (P=0.002 and P=0.01, respectively). A statistically significant number of non-classical monocytes contained SARS-CoV-2 S1 protein in both severe (P=0.004) and PASC patients (P=0.02) out to 15 months post-infection. Non-classical monocytes were sorted from PASC patients using flow cytometric sorting and the SARS-CoV-2 S1 protein was confirmed by mass spectrometry. Cells from 4 out of 11 severe COVID-19 patients and 1 out of 26 also contained SARS-CoV-2 RNA. Non-classical monocytes are capable of causing inflammation throughout the body in response to fractalkine/CX3CL1 and RANTES/CCR5.
==============


PairTheBoard

Article on developments for Longhaulers treatment.

https://www.verywellhealth.com/long-...-story-5189914


PairTheBoard

Wall Street Journal story on why approved Covid therapies are so limited.


https://www.wsj.com/articles/covid-t...ms-11627312440


PairTheBoard

Check this 6 minute viral clip out. I haven't tried to verify his claim of ADE which is a big claim.

https://twitter.com/PaintInWords/sta...352924672?s=19

Debunkings ongoing

kinda surprised that no one in this thread ever brought up remdesivir and wanted to talk about why the results were so mixed.

Sept 2021, Lancet published study of Remdesivir

"In this randomised controlled trial, the use of remdesivir for the treatment of hospitalised patients with COVID-19 was not associated with clinical improvement at day 15 or day 29, nor with a reduction in mortality, nor with a reduction in SARS-CoV-2 RNA,” the authors concluded. “Together with previous evidence, results from the DisCoVeRy trial do not support the use of remdesivir in hospitalised patients with COVID-19 in a population with symptoms for more than a week and requiring oxygen support.”


https://www.thelancet.com/journals/l...485-0/fulltext


PairTheBoard

I've heard charges that the study FDA went by was an adaptive study where endpoints were changed at interim looks. However, I don't know if that's accurate nor how it would have affected the p-values. IMO, it deserves an investigation.


PairTheBoard