Quote:
Originally Posted by TomCowley
Could have a combo of metabolic and respiratory acidosis here, guy goes sleep apnea and can't breathe much or something, and kidneys obv not at full function.
The cool thing about this case was how everything all made so much sense in the end.
Our patient just had his kidney removed and it looks like maybe the other kidney isn't in the best shape. The high potassium, high creatinine, and furosemide drip all point to this. The low bicarb is the result.
So our damaged kidney isn't able to resorb bicarb and we get a
metabolic acidosis. This causes his blood pH to start dropping. This body responds by hyperventilating a bit, breathing off extra CO2 and giving himself a compensatory
respiratory alkalosis. This raises his pH back towards homeostasis and he's not really showing any ill effects (my guess is he's chronically acidotic but that's neither here nor there).
So what happens? This big, obese guy with an apparently challenging airway goes to sleep in a hospital bed on his back. Maybe he's even sloshed from surgery and all the drugs we've given him. He has
sleep apnea and now hypoventilates. Instead of fighting the metabolic acidosis with the compensatory respiratory alkalosis his lungs are actually making things worse with their own respiraotry acidosis. His pH quickly drops and he loses conciousness. In fact, his apnea is so bad that once his brain can no longer wake up to breathe he quickly desats and sets off the alarm, beginning the code.
Anyway, thought it was a cool case. Had nobody to talk to in the middle of the night, made thread.