You are almost always the only one with a set because it's high low. And you got a backdoor nut flush draw and backdoor broadway draw.
You could even have the best hand right now.
If not, I see you're getting >4 to 1 for the main pot and 2 to 1 for the side pot.
Most likely one guy has a straight and the other dude has a nut flush draw for the side pot, which makes it a breakeven call, or better if both have a straight and neither have a flush draw.
But for the main pot you have better equity vs the likely hands of your 3 opponents than the price you are being laid, which makes up for the main pot only being break even for you. It makes it profitable.
Assuming you have no cares about bankroll, this is a call.