Which 5- cardwraps are playable in Big-O? Which hands are playable always? Which ones are based on position and number of players?

I am referrring to starting hands. I.e "A2345", "23456", "9TJQK"

Uh.. I guess A2345, 23456, AKQJT, and KQJT9.

I wouldn't want to mess with 34567 when a better low is so likely and you're playing for half at best (and I would advise extreme caution with 23456 as well). And same problem with QJT98 because it needs to hit the higher end of a straight and that usually includes a low. I suppose the latter is more marginal.

5-Card Omaha Hi/Lo Simulation ?
292,862 trials (Randomized)
Hand Equity Scoops Wins Hi Ties Hi Wins Lo Ties Lo
Jt987 31.13% 54,351 121,256 6,355 2,622 230
A2xxx 36.39% 47,747 62,423 9,996 103,528 34,642
Aaxxx 32.48% 53,140 96,257 9,606 28,397 34,659
Notes/Warnings
You have selected a five-card omaha variant with five cards before the flop

5-Card Omaha Hi/Lo Simulation ?
462,846 trials (Randomized)
Hand Equity Scoops Wins Hi Ties Hi Wins Lo Ties Lo
Jt987 33.23% 95,327 203,192 7,764 4,065 261
A2xxx 29.44% 47,731 86,053 21,340 52,259 169,681
Aa2xx 37.33% 81,643 150,288 17,636 31,727 169,647
Notes/Warnings
You have selected a five-card omaha variant with five cards before the flop

1. i doubt those are the simulations you actually wanted.
the 'xxx' you added to A2 and AA means those three cards may be selected of random ranks but they are to be of the same suit. likewise the "xx' you added to AA2 means the 2 cards are to be of the same suit.
if you want random cards, without constraints put on their selection just leave the AA2 or the AA as is, if visually you require to see indications of 5 cards the proper syntax then is A2***.

2. if you are going to post PPT simulations then the following is instructions to post them properly.
- under the simulation you will see "2+2", it follows "Edit" and "Link".
- click on the "2+2", and a text box appears
- select all, and copy the text.
- paste the text into your thread post/reply.

ProPokerTools 5-Card Omaha Hi/Lo Simulation

600,000 trials (Randomized)

Hand	Pot equity	Scoops	Wins Hi	Ties Hi	Wins Lo	Ties Lo
jt987	29.87%	108,126	236,607	12,360	5,711	465
a2	37.11%	103,744	136,104	17,083	213,856	67,668
aa	33.02%	112,683	204,391	16,627	57,856	67,708

3. since it would appear you differentiate hands by card ranks without consideration of suitedness, you are asking a question concerning 10 hands out of a possible 6175.
with consideration for distinct suitedness you are asking concerning 10240 hands (5 card rundowns w/o a gap, 6 different suitedness configurations) out of a possible 145,041 distinct hands.
your question concerns hands that amount to less then 4 of each 1000.

My first troll. Thanks for the corrections/comments. I'm a newb to 2+2

All except 6789T

34567 is a really good hand imo

I would say it's opponent dependent...I play in a home game where players will stack off with top set/no low when a wheel flops! It's pot limit fwiw.

Or players will call off with open ended straight draw vs wrap.

But, in any Omaha HL game, the general rule of thumb is play with Ace and wheel cards/suited or with all big cards. Basically 6, 7, 8 and 9 are garbage cards.

three two with high wraps are great if it is cheap and an ace flops. eg QJT32, opportunity for double nuts