This from Wiki is actually pretty interesting, I didn't know the story of Jackson's wife:
Quote:
The campaign was very much a personal one. As was the custom at the time, neither candidate personally campaigned, but their political followers organized many campaign events. Both candidates were rhetorically attacked in the press. Jackson was strongly attacked as a slave trader, who bought and sold slaves and moved them about in defiance of higher standards of slaveholder behavior.[60] Matters reached a low point when the press accused Jackson's wife Rachel of bigamy.[61] The accusation was technically true; it was based on the legal status of Rachel's marriage and divorce from her former husband many years prior (1791 to 1794).
Rachel Jackson had been under extreme stress during the election, and she never did well when Jackson was away at war or work. Jackson blamed John Quincy Adams because Adams's supporters had repeatedly attacked the circumstances for Jackson's wedding to Rachel. Jackson described her symptoms as "excruciating pain in the left shoulder, arm, and breast".[62] After struggling for three days, Rachel finally died of a heart attack on December 22, 1828 three weeks after her husband's victory in the election (which began on October 31 and ended on December 2) and 10 weeks before Jackson took office as President. A distraught Jackson had to be pulled from her so the undertaker could prepare the body.[62] He felt that Adams' accusations had hastened her death and never forgave him.[63] Rachel was buried on Christmas Eve. "May God Almighty forgive her murderers," Jackson swore at her funeral. "I never can."[64]
So by "they destroyed her" Trump he means "said true but mean things about her husband and herself"? That's being pretty charitable, I assume Trump couldn't tell the story himself, this is some weird third-hand thing where Trump had a talk with someone angry about putting Tubman on the 20.