Listening to Carroters (Peter Clarke) podcast pointed me in the direction of this.
"Issue 1" of what appears to be an "E-Magazine" series has been released and Carroters looks at a broadway flop BTN v BB in a single raised pot. He looks at the difference between the GTO option that PIO offers and where the population differs. He then looks at ways to exploit this gap.
I really enjoyed working my way through it, PIO on in the background as well makes this a great interactive study tool.
I won't go into too much detail about the observations he makes (and the relevations!!) but the way he sets it out with small screenshots of PIOs results makes it really easy to understand.
How regular this will be, I don't know. It's given me a lot of food for thought.