Lets say you are the button in a 1/2 cash game (all stacked at about 300)
UTG+1 bets 12 and middle position calls. It folds to you. Do you call raise or fold ?
I think I fold unsuited but not sure i would want to raise here ?

What happens if you raise?

It depends. How much do you know about UTG+1?

ummm not sure ? maybe you push the blinds out and get called by 2 peeps ?
maybe you get raised ?
Lets assume that UTG +1 is a TAG but not a maniac.
I am thinking middle position is NOT on AA KK QQ or even AKs or they probably do more then just call the original raise.
I mean if you just flat call do you think you need a FLOP like K 10 5 or Q 6 2
to call or raise any cbet ?

OK, now you're starting a better thought process.

If you call and keep the blinds in a the flop hits you hard, maybe you can win a bigger pot (so ask yourself, how sticky are these players on a wet board?)

If your read on the original raiser is correct, you can comfortably 3-bet and fold to a 4-bet, or, if just called, steal the pot on a dry, ragged flop.

It still depends on making a judgment call on your opponents, but that's the way to approach the problem.

With the limited information you have provided I would assign utg+1 a tight opening range and fold in this spot. You'r getting into a world of hurt when you flop TPTK and villain has [AK, AQ]. Even with your blockers this is a significant part of his utg opening range. It's highly likely that you'r behind his entire opening range from that position.

If UTG+1 is TAG then with KQs I'm gonna 3-bet. If he re-raises, I'm done and out of there. If he calls and the board is low, I'll fire again. If it's a broadway friendly board, I'm shutting down unless I flop a miracle two pair or straight. Checking behind if I can, folding if TAG bets.

End goal with TAG UTG+1 is fold him out or lose the minimum with a less than premium hand. Consider it building a baseline, so in future when you get it in good with him, he's willing to press hard and you can walk the dog.

Mind you, folding is fine too - and if you're too afraid to 3 bet, you should def fold. Calling is awful.

I agree with Greebo. Im coming in for the 3 bet most of the time.

VS a 4 bet and cold call by MP i am out.

You can also reraise a dry flop to give yourself a chance to let the turn be a x/x street and re evaluate on the river.

Huh??

OK, you've 3-bet pre, and been called the original raiser and the cold caller.

The flop is dry. original raiser bets, cold caller raises, and now you 3-bet again?

I'm not a fan of the re-raise the dry-flop idea either. If you 3bet pre, and you get called apparently in this instance by not 1 but 2 people, and then the early position donks out and MP calls?

KQs dead in the water so you're on pure bluff here and asking to go spewy.

The point of the 3bet pre is to do two things:
1) Fold better hands like small pairs;
2) Give yourself a chance to get away from it with the worst hand for as cheaply as possible.

If you flat with KQ you're asking to be c-bet into, and on a dry board you're likely to call the flop bet for about as much as a 3bet would cost, and put yourself in a situation to improve into the worst hand on the turn, costing you more money.

3betting KQs pre will also fold out worse hands - so with a marginal hand like KQs you have to assume you're already beat and you're up against someone who isn't folding easly.

Don't spew to the calling stations.

What room are you playing 1/2 where you're going to run into a TAG on a regular basis? Almost nobody is a TAG at 1/2. Everyone is either a tight passive or loose passive. For KQs to be ahead of a raise, the UTG+1 has to be raising about 20% of hands. That's not a tight player in anyone's book.

Unless I have a read that the villain is a near maniac, KQs goes in the muck against a UTG+1 raise. Now if I have 76s, that's a different story.

You're kidding right ?
I guess you never played a game during the middle of the week (in the day time) in Atlantic City. There are at least 2 guys at every table that are locals just burning time for their comp hours.
These guys (when it comes to pre flop) will play Only AA KK QQ AKs AQs maybe AJs and JJ exclusively.

If you are going to fold KsQs on the button with 2 raisers in front you are not going to win a ton of money. Yes original raiser has a lot of AA/KK/QQ/JJ but also all pairs, if he is tight live player maybe not all but has 99/88/77,QsJs,Js10s ect, while caller has a lot of small pairs, some suited Aces and connectors like 89,910,j10, so against their ranges and odds you are getting you should at least make a call. Problems of raising comes from when you get 4bet by UTG opener than his range has us crushed pretty much, and we fold a great potential hand , calling is a decent play looking to see flops.

Especially live where blinds are not as likely to raise but are more likely to call and bb just check looking to see flop and making your odds even better, i would never fold preflop on that action, so call is standard without any reads.