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Coronavirus Coronavirus

06-04-2020 , 10:23 AM
Quote:
Originally Posted by Onlydo2days
1300 deaths in Brazil today seems to hurt the hot weather helps stop the virus spread arguments, am I wrong?
its not really very hot at all in the major cities there, about the same as we have been getting in Canada the last couple weeks. 67 degrees in Sao Paulo right now at 11:30am. I was down there in the southern half from Sao Paulo to Floripa May/June a decade ago and wish I had brought more cold weather clothing.
06-04-2020 , 10:26 AM
Quote:
Originally Posted by FallawayJumper
where are all the geniuses who were touting Sweden's no lockdown policy now?
Those people were being patient and waiting for a clearer picture, noting that it's entirely possible Sweden got it right and everyone else wrong. I would not have bet on Sweden, but I also don't think it was unreasonable to give them a listen. Economic harm is a part of the equation and shouldn't be outright ignored...

This article is just a reflection of the fact that the picture is clearer now than it was before. Yes, Sweden admits they ****ed up. It is clearer now than it was before. Shrug

I don't really think that's an indictment on the US either. It is easy to go full ToothSayer on the country, but he himself knows very well the makeup of the country and that the populace is rife with idiots. The difficulty lies in governing. It really doesn't matter who the president is. This place is impossible to govern
06-04-2020 , 10:37 AM
Quote:
Originally Posted by TeflonDawg
Some of Those people were being patient and waiting for a clearer picture, noting that it's entirely possible Sweden got it right and everyone else wrong. Most were just being just the flu bros
fyp
06-04-2020 , 10:52 AM
Fair. I wasn't really paying any mind to flu bros because they're literally denying reality
06-04-2020 , 10:53 AM
Quote:
Originally Posted by PuttingInTheGrind
Former Mi6 boss Sir Richard Dearlove belives that the virus was an accident that originated from a lab in China.

https://uk.yahoo.com/news/exclusive-...124812559.html
75-year old guy figured it all out from his rocking chair
06-04-2020 , 11:43 AM
Quote:
Originally Posted by ToothSayer
FallawayJumper,
Nice to see you reading real news rather than fake news. If someone told me in 2010 that Fox News would be far more reliable than the NYT in 2020 I'd have laughed in his face. Yet here we are. Weird world.

From the study it looks like hydroxychloroquine had a 16% lower rate of symptoms 4 days after exposure (probably too late to prevent symptoms, the virus is already well through the system by then). So a much better result than placebo, but the overall infection rate was so low in both groups it didn't reach statistical significance.

So the jury is still out on it. The conclusion we can draw from the study: It doesn't provide a very large benefit in initial symptom display taken 4 days after exposure. It may provide a moderate benefit (number needed to treat: 6, better than most drugs by far).

this is what some experts have said re the study
I cannot provide a source because the guy who posted it on a different forum didn't provide the source
but I don't believe he made this stuff up - it passes the smell test


“As we say in Tennessee, ‘that dog won’t hunt’ — it didn’t work,” said William Schaffner, a professor of preventive medicine and infectious diseases at Vanderbilt University Medical Center. "

"Jeanne Marrazzo, an infectious-disease expert at the University of Alabama at Birmingham, said the results “should provide a very big nail in the coffin” for the idea that hydroxychloroquine can help prevent covid-19."

"David Boulware, an infectious-disease specialist at the University of Minnesota and the study’s senior investigator, said he launched the trial because hydroxychloroquine had shown signs in a lab setting that it might be effective against the virus."......so he was hoping it would be effecitve, but alas, it was not."
06-04-2020 , 12:06 PM
So, I am hearing through the Grapevine that NYC, especially Soho, has had MASSIVE looting that is being very underreported by the MSM.

Any locals with firsthand knowledge want to confirm or deny? I am asking here because I think the people in this subforum do a much better job than most separating reality from political ideology. Probably because BFI attracts people who realize money talks and bullshit walks.
06-04-2020 , 01:01 PM
06-04-2020 , 01:13 PM
Quote:
Originally Posted by Kelhus100
So, I am hearing through the Grapevine that NYC, especially Soho, has had MASSIVE looting that is being very underreported by the MSM.

The New York Times, one of the main targets of those who say the MSM is fake or extremely biased news, has reported extensively on the looting in NYC. search and ye shall find





https://www.nytimes.com/2020/06/01/n...-protests.html
06-04-2020 , 01:18 PM
Maybe it's because I live in NYC, SoHo/5th Ave looting is all over my news feeds.
06-04-2020 , 02:53 PM
Quote:
Originally Posted by David Sklansky
That is not a good argument when the subjects are voluntary, young, and apt to get it (randomly and most likely with a larger viral load) anyway. Even more true if there is indeed a good chance for a big upside for the world.
You should probably also consider that health care workers would be handling live CV, which poses quite a bit of risks on its own. Also, that keeping the virus "live" probably requires some special handling, not generally part of standard health care protocol. Additionally, you would likely need to "manufacture" live CV to satisfy the demands of inoculating these individuals. I assume that more CV in the world increases risk of mutation to possibly more virulent strains. And your base assumption may simply not be true, or at least not known to a reasonable degree of accuracy.

I'm not really arguing against your idea, I am simply pointing out some of the risks in pursuing it. Your general idea of creating a farm of infected (but recovered) individuals that could help others seems worthy, but similar to development of vaccines, it needs a sound plan to implement, as well as some quantitative analysis to assure that the benefits outweigh the risks.
06-04-2020 , 02:57 PM
Quote:
Originally Posted by chytry
75-year old guy figured it all out from his rocking chair
Yeah, it's pretty obvious at this point that we'll never know the truth on the origins of CV.
06-04-2020 , 02:59 PM
Quote:
Originally Posted by FallawayJumper
The New York Times, one of the main targets of those who say the MSM is fake or extremely biased news, has reported extensively on the looting in NYC. search and ye shall find
I would only hope that the New York Times would be reporting on major events in New York City.
06-04-2020 , 06:16 PM
Quote:
Originally Posted by ToothSayer
From the study it looks like hydroxychloroquine had a 16% lower rate of symptoms 4 days after exposure (probably too late to prevent symptoms, the virus is already well through the system by then). So a much better result than placebo, but the overall infection rate was so low in both groups it didn't reach statistical significance.
this is data. doesn't look promising to me.

06-04-2020 , 07:09 PM
NBA resuming in July

22 teams all playing in Orlando if I read that right

I don't think it's going to work

Quote:
The NBA said the season resuming is contingent on an agreement with The Walt Disney Co., which owns ESPN, to use the Walt Disney Resort for all games, practices and housing.
There's no way that's going to work
06-04-2020 , 07:17 PM
Quote:
Originally Posted by bucktotal
this is data. doesn't look promising to me.
Right, but this is the headline:

Quote:
Hydroxychloroquine fails to prevent coronavirus symptoms, researchers say
And these are the expert (and course moron level wrong) comments:
Quote:
“This was a large, randomized controlled trial done by very good people. Hydroxychloroquine did not provide a notable advantage,” Dr. William Schaffner, a specialist at Vanderbilt University, said.
It wasn't a large trial because most people never got corona (had no infectious dose) and thus aren't even trial participants except in the headline. Here is the correct take:

In a small trial of 100 people, given the drug for the first time at least 4 days after being infected, the data showed that 16% more of the hydroxychloroquine group were symptom free than the control group, although the trial was too small for statistical significance. The 95% confidence interval was 50% fewer to 13% more among the chloroquine group. The study did not consider symptom severity, only the binary appearance or non-appearance of symptoms.

That's the correct summary. It's close to meaningless and shows nothing except that a prophylactic isn't likely to stop all symptoms in >50% of takers when taken four days after infection. That sentence is the only takeaway from this study.

I agree in general that hydrocholoroquine is probably not a great deal of help - we would know by now if it was from clinical experience (many doctors swear by it, but that doesn't mean much, we would have more than that by now) - I only object to the silliness of claiming this study shows something, or like the moron at Vanderbilt, that this is a "large trial".
06-04-2020 , 07:50 PM
Quote:
Originally Posted by TeflonDawg
NBA resuming in July

22 teams all playing in Orlando if I read that right

I don't think it's going to work

There's no way that's going to work
Why wouldn't it? Pretty sure disney owns like 20+ hotels in orlando and the espn sports complex to host it.
06-04-2020 , 11:41 PM
Quote:
Originally Posted by AllinPoker
Why wouldn't it? Pretty sure disney owns like 20+ hotels in orlando and the espn sports complex to host it.
Orlando area hookers up 469% after hours.
06-04-2020 , 11:46 PM
On a more serious note, has anyone looked at the antibody treatment that Sorrento is working on? I'm trying to figure out if this is legit or a pump and dump that's already been dumped. Here's the link:

https://investors.sorrentotherapeuti...y-develop-covi
06-05-2020 , 12:17 AM
Quote:
Originally Posted by bucktotal
this is data. doesn't look promising to me.

'Not promising' is being rather polite...
06-05-2020 , 03:59 AM
Interview with someone from AZ on the BBC this morning regarding the oxford vaccine

They're starting trials in Brazil to get faster results.
06-05-2020 , 06:29 AM
Quote:
Originally Posted by TeflonDawg
NBA resuming in July

22 teams all playing in Orlando if I read that right

I don't think it's going to work



There's no way that's going to work

Why not? Seems like a really creative solution that all sides win in.

Players are on the road non stop during the season. Having several basketball campuses seems like a great idea. Giving families an option come for a few summer months will be a treat.

Very little chance this fails imo.
06-05-2020 , 07:34 AM
Quote:
Originally Posted by FallawayJumper
...........................

where are all the geniuses who were touting Sweden's no lockdown policy now?

from the article:

"Deaths in Sweden, though, have been eight times higher than in Denmark and 19 times higher than in Norway, even though Sweden is only double each neighbors’ size. The outbreak appears to be continuing to course through their society, even while most other European countries seem to have gotten things under control, at least for now."


https://www.washingtonpost.com/world...482_story.html

Hi,

sorry but this would seem to be an extremely misleading and out of context quote, would you like to explain further why that isn't the case please?

Sweden has around 4500 deaths from CV currently but quoting that raw number and comparing with other countries would seem to be at best stupidity and at worse extreme bad faith on the part of the journalist. You can see here that approximately 90% of deaths are in over 70s, 95% in over 60s and 99% in over 50s:

https://www.statista.com/statistics/...by-age-groups/

Average Life Expectancy in Sweden is 82 so clearly is it mostly killing older people where there will always be an eventual cause of death whether CV or something else. This also doesn't cross reference with comorbities or high-exposure risks which likely contribute to a lot of the relatively lower age deaths.

Here is average deaths in Sweden for 2020 vs the average of 2015-19:

https://www.statista.com/statistics/...aths-per-week/

As you can see 2020 was below average earlier in the year, then spiked up with CV deaths and is now rapidly heading back to normal or below. If we assume Q4 of 2019 was also below average are we really sure it isn't at least partly a displacement of deaths from those who 'got lucky' surviving the traditional flu/winter season then very unlucky with a serious novel virus emerging in Q2 2020? Or that the 2020/1 flu/winter season line isn't going to also be below average because some more people got 'unlucky' now with a serious novel virus who would've died then?

Happy for someone to explain to me why that isn't the the case but what I am mostly seeing here is editorializing/stupidity/bad faith on the part of the journalist whereas the actual context is a Scientist trying to have an honest and open discussion about what could have been done better (eg. locking down care-homes, which few large Western countries seem to have done well even with hard-lockdowns).

Here is a response to this sort of news coverage which also briefly touches on suggestions that serology results may present a lower bound for immunity rather than a higher one, since many areas/scenarios seem to top out around 20% on antibody results and we may have other forms of immunity, which it would also be interesting to see some discussion of here:

https://www.telegraph.co.uk/news/202...readed-second/

And finally to balance things out a bit on the behalf of the Swedish scientist, here is the PM of Norway wondering if their lockdown was excessive:

https://www.telegraph.co.uk/news/202...e-like-sweden/
06-05-2020 , 07:43 AM
So TS, wanna make a bet on the vaccine?
06-05-2020 , 08:04 AM
Quote:
Originally Posted by RikaKazak
So is it pretty much a fact at this point that the bigger the viral load you're originally exposed to the worst the symptoms?

Or is that still a "meh theory" at this point?

I tried google but it's so hard nowadays to find legit info with all the click bait bullshit people put out nowadays. I miss the old internet when it was mostly us nerds
One small study from Vietnam:

Quote:
Compared with symptomatic individuals, asymptomatic people were less likely to have detectable SARS-CoV-2
Quote:
NTS viral loads fall faster in asymptomatic individuals, but they appear able to transmit the virus to others.
But it doesn't exactly tell us what viral load they started with.

https://academic.oup.com/cid/advance...iaa711/5851471

      
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