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Originally Posted by IntheNow
Just to be clear, one shot of Pfizer after a few weeks is very similar protection (just slightly less) to “fully vaccinated” after 2 shots, right?
Correct. And the UK scientists take that stance - they don't do second vaccination for 12 weeks even with their crappy vaccine because the first does a pretty great job of protection for the bad outcomes, which are what matter.
The policy around the immediate need for a rapid booster was based on comically faulty science where they didn't give the first shot enough time to work - so they were comparing two weeks old first shot with 4 weeks of first followed by second shot. But if you let the first shot run its course (no second shot) for long enough (4 weeks), the protection of the second shot only adds a few percent. There's no good case for it in the few months following the first shot.
As far as I'm concerned the second shot within weeks of the first is another example of comically shoddy science and/or fraud from the experts. In the UK for example, Birmingham University finds
this:
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Antibody response in people aged over 80 is three-and-a-half times greater in those who have the second dose of the Pfizer COVID-19 vaccine after 12 weeks compared to those who have it at a three-week interval, finds a new study led by the University of Birmingham in collaboration with Public Health England.
So the vulnerable actually get far BETTER antibody response by waiting more than 3 months for the booster. Just totally incompetent waste of precious vaccine because the experts in this field are like Elrazor and can't add up or think.
No one is really studying this stuff properly (because they'd rather do gain of function research that causes millions dead and trillions lost and a global pandemic, then lie about it, and or go out finding bats to
get golden showers from).
But in the absence of good data and with all the data pointing the same way, the money line for Pfizer is pretty strongly on waiting a good while for your second booster, both for the public good, giving others a chance for protection, and to get a better response yourself.
In the long term (many months away), the booster shot is likely to give you longer lasting immunity of a higher quality. So while it makes sense to get it eventually, I'd say it's >90% that waiting 3 months will give you a better immune response. In the short term (less than a few months), there's no good reason that I can see to get the second shot, and lots of reasons not to.
Interestingly, we see the same with prior immunity: Those who previously had covid months ago and have the first vaccine get antibody levels well the above the quality of naive (never infected) first + second vaccine recipients. My guess is this has something to do with the longer time interval, the same mechanism as the geriatric study above. But expert scientists being wagon circling morons with slow wits and slow to admit their mistakes and change policy, it will take them months more to figure this out.
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I’m 4 days away from due date for 2nd shot and I’m having a hard time deciding to get it or not. I was on fence for first already (I’m 36 and healthy) and now knowing 2nd shot doesn’t add much extra protection/I’ll likely be sick and out of commission for a day or so/there’s some tail risks to potential over dosing of this vaccine in general/we found out the spike protein with this particular vaccine does (always? Sometimes? IDK) make its way to rest of body and not just stay in area of injection like they (FDA) had hoped, makes me really lean towards not getting it.
I can't see any good reason to get the second shot at that age and healthy.
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Seems to me if this wasn’t a rushed pandemic situation, the vaccine (at least Pfizer and moderna) would have been one shot like usual vaccines and that this is very likely being over dosed to the population (especially non-old folk).
Also, isn’t one shot of Pfizer more protection than Johnson and Johnson? If so, why the f*** am I not considered fully vaccinated and they are?
Really appreciate any responses. This has been on my mind a ton past couple weeks. My wife ended up cracking a few days ago and got 2nd due mostly to family/societal pressures.
Vaccine bigotry is a real thing in the US, all driven by batshit crazy left wingers who demand compliance or else. Watching from other countries, it's a weird phenomenon. Hopefully the US left wing grows out of its idiot/loser phase.
Texas is a perfect example of how these left wing clowns and the best experts fail out and get it wrong on an epic level. You want to listen to them on immediate second booster as when ALL the data is against it as well? I don't.