There are genetic factors that can cause obesity, such as genetic mutations that cause the body to produce little/no leptin or a defect in the receptor for melanocortin (both appetite suppressors). However, like many genetic disorders, these examples are fairly uncommon.

There are also epigenetic factors. These have been studies extensively in rodent models and through observational studies on human populations. Typically those exposed to famine early in life can develop eating disorders later in life. This effect is thought to be due to epigenetic modifications and lead to transgenerational inheritance.

Little is known about the effect of a western diet on the susceptibility of offspring to inherit genetic modifications that may leave them susceptible to obesity. However, there are populations that are at increased risk of obesity due to sudden environmental changes forcing changes in eating behaviour that is associated with obesity (e.g., Pima Indians of Arizona).

AZN's vaccine is better.

Well a bunch of you guys (including you) were talking about how hospitals were going to get overwhelmed, and with North Dakota having the most covid cases per person it seems reasonable that it would happen there first right?

And I'm saying no hospitals are going to get overwhelmed.

And if the active case numbers go down, (because the new case number is low), then that puts less pressure on the hospital and hospital numbers go down.

Getting obese is mostly a lifestyle problem. But if they stay obese too long (like more than a year) it becomes a trap/disease they can't get out of. Because once the obese fat cells lose a certain amount of fat, sooner or later the body goes into starvation mode and greatly increases hunger hormones and slows metabolism.

The main reason the VSG type of bariatric surgery works well for five years or so is because it stops the stomach from pumping out hunger hormones. That is why virtually no obese people are able to lose weight and keep it off without bariatric surgery.

Mouse studies have also shown obesity is contagious and it has to do with gut bacteria. It's not just lifestyle and genetic, although that also plays a big role.

None of this applies to people who only have small amounts of weight to lose; they can lose weight and keep it off without their body going into starvation mode, which is why they think it's easy for obese people too, but it's not.

The more other countries start eating processed foods with high fructose corn syrup and other garbage the more they will start having the same problems.

ND Hospitals are very close to maximum capacity and many have implemented surge planning, such as allowing asymptomatic nurses to keep working and cancelling all non elective surgery. Some hospitals are having to send patients to other sites.

The problem is not just with beds but with staffing, capacity can be seen as licenced, which states the maximum operating capacity and staffed which means the actual on the ground capacity because a bed is just a bed with no professional staff.

It was because actual staffed beds were running out that asymptomatic nurses were asked to keep working.

Just google ND ICU beds if you doubt the above.

Also your hypothesis is fundamentally flawed from a data point of view.

Even if the average rolling daily rate of new infections has decreased, this daily case load will still be adding to the burden on hospital capacity as long as new hospital cases occur at a rate faster than old hospital cases resolve.

There is also a lag between positive test and hospitalisation, so there is still a large influx coming down the pipe as the peak of 7DRA was Nov 20th.

The 7 day average is still relatively high compared to other periods in the pandemic and is still higher than it was at the beginning of this month.

People in critical care is still increasing every day in USA, until it stabilizes lets refrain from bragging that everything is fine?

USA might also overtake Europe this week in terms of total number of critical care patients, while Europe has 2,2ish x number of inhabitants.

The only mircale about USA figures I don't understand is how death figures stay so low. Will be very interesting to see what happens today & next few days since weekend figure days are now over. I am expecting >2k deaths today, but lets see.

D- level trolling. Yawn.

See this is the problem with obesity, we have written a million articles and studies about how it might not be the obese person's fault they are obese.

Fat people walk around literally thinking they can't do anything about it and there's plenty of studies out there reinforcing this mental state of mind.

If your body is in starvation mode, eat even less!

Life is actually so simple and the answers are all out there, we just complicate it because we want to make excuses for the mentally lazy.

There was a twoplustwo ott poster that was obese and argued with 2+2 about it being genetic. He got fat shamed constantly and was told to track his calories every day and eat less.

He did that and lost a huge amount of weight. That's literally how losing weight works. Track your calories, eat substantially less. The end.

As you always demand of others, show us your work.

Show us you are not operating on an infinite bed or staffing capacity.

Show us that no hospital will ever get over run if these levels either keep rising, or flatten out or lower but remain at a high input level.

I've pointed this out since the beginning with these super high inbound patient rates, that if hospitals cannot discharge patients at a rate faster than or equal to the inbound rate, they will eventually become over run unless you operate under the mistaken belief they have infinite bed capacity by just adding more temporary beds. In which case you need to address where they get that staff.

And this is much different than the long summer high internment rate as now with the virus almost everywhere, the ability to swing people to nearby hospitals in other cities or States is comprised as they are almost ALL filing up. That limits being able to parachute in staff from other areas too.

So show us your work that supports that statement that they will NEVER get overwhelmed.

And understand that if you are calling for all governments to take a course of action of 'let it rip', 'herd immunity', based on a position of 'the hospitals will not get overwhelmed', the burden of proof is on you and it is very high as being wrong with regards to an exponential growth virus by even a few days would be catastrophic.

So if you are going to state your position is the correct one and should be followed then you need to show your work.

You have convinced me. Opiate users should be provided pharmaceutical grade dope administered by professionals.

Italy 3rd highest new reported deaths since beginning of the outbreak today.

I thought Europe would peak in death this week. They still might, but it's still increasing in lots of countries.

umm you must be slow.

I'm legitimately saying to tell the person you're dealing with to move back. Sorry you're too beta to assert yourself.

One day you will be a big boy.

I appreciate your concern by the way.

The kiddie table is over there and there is a seat waiting for you.

One day you will be able to contribute at the adult level.

Highest number of deaths since beginning of the outbreak reported today.

Strong skills.

USA might overshoot 2k deaths by a bit today.
Wouldn't be surprised if 7-day avg moves to 2k in the next 7 days.

He called people pussies because he's arrogant.

There are people his age and health profile who have died running their mouth in the same way.

I mean, it's not like he's wrong to an extent, but the abrasiveness...the dismissiveness...

For all he knows, he could contract it tomorrow and be dead in 3 weeks. And he can lend a cocky smirk while reading this, not realizing that the simple possibility that his local hospital could be overflowing and unable to accept him as a patient is what could kill him, not his apparently superb health profile

I wish no such thing on ANYONE. I understand for most it's a nothingburger. He should understand that people EXACTLY like him are dead. He is not bulletproof, and people elsewhere really are going through the wringer, either with C19 itself or friend/fam or as medical personnel

Go up to them and call them pussies for politely asking us to distance, mask up indoors, and wash our hands...Like, c'mon man, not necessary. We can emphasize being rational while also not being condescending douchebags, or so cocky the very mentality actually kills

What he said was true...

Just because you and others absolutely hate him doesn't mean he's always wrong

If anything, this post just makes you obsessive and more interested in the poster than what was actually posted

I would say many of you have your heart in the right place imo, but the head? Y'all too emotional sometimes. And all it does is give ammo to the callously indifferent and trolls. You can't win that battle, you can only lose and you are losing

Exactly. But is has become more important to be petty and just argue, never mind that the post laid out several perfectly reasonable and true statements

It's like people are incapable of letting the readers decide for themselves what information to absorb and discard or explore on their own...I'm well aware ToothSayer is wrong about stuff, I don't need immature and obsessive people screaming at the top of their lungs beating on straw men and deliberately obtuse admonishing of his posts...

Honestly I'd rather you both go away. You're just annoying and about to end up on my ignore list. At least with ToothSayer I've learned things. I can also spot his bullshit and don't lose my **** when he goes full bad faith, so I don't need to ignore him

Seriously, some of you might really be addicted to 22 or have a serious problem with the mentality held while reading these threads. Keep in mind this is not politics forum, it's BFI. But that seems lost on many posters here

Thread has gone full aids and it would be nice if people just went to the politics COVID thread, or to Unstuck. TS ain't there, go ***** about him over there ffs

Tooth likes to engage in debate and the easiest way to do that is often throw out controversial statements and then debate on it.

He keeps hooking the fish in time after time after time. I don't think he particularly cares if a few controversial statements of his ends up being wrong.

Incredible.

Describing obesity as contagious is beyond dumb and those white knighting for this phraseology are pumping forth white hot hot takes like a geyser at Yellowstone.

Bad arguments are bad arguments, it has nothing to do with rage, this is just onboarding the narrative of the person who shouts the loudest and insults the hardest and weaker minds are influenced it seems unduly by the primordial signalling of such base behaviour.

Those of stronger more mature rational minds, see a spade for a spade.

Read the original post. All he was saying is that parents really do spread obesity to their kids, just not in the literal way that several posters now have acted like he was saying. They're being intellectually dishonest

He basically said parents pass their bad habits and/or genes to their kids, and also that there was a time where people were led to believe trans fats were not the poison we now know they are, sat fats to be avoided...

That's it. He takes the avenue of utmost dickishness in the process, but there was absolutely nothing wrong with what he said. But people just go on about it anyway...

If we were having a more general conversation, it could pass as a bad use of language.

In a thread devoted to the most dangerous contagious disease of a generation, not so much.

Anyone who cant see this is simply a mental midget.

Hewasbeinganidiotonpurpose.jpeg

I know he doesn't care. It just amazes me how many people don't realize how they contradict themselves and their own use of time arguing with who ultimately amounts to a brick wall

The stupidity is astounding, and I say that as someone who actually agrees more often than one might think with those who are obsessively mashing the keyboard instead of going outside and letting the sun shine on their face for even 5 minutes. Sheesh. Go get laid. It's not hard even in the COVIDpocalypse...