I just ran into this article that might be somewhat related to what might happen in the brain when playing vs. humans and not bots.
https://www.news.com.au/world/breaki...c5a26abae32130
To me, all humans are different but the bot or so that one plays against is always the same. That is why one needs to consider a more conservative strategy vs. humans compared to vs. bots, as a big mistake is easy vs. humans.
If you would know one player as well as the bot or so, then it would be somewhat similar but the humans adjust and the bots or so might not, and the humans view the situation different from the bots or so and one knows that one is less likely to pull off some obvious looking bluff vs. a human.