I would guess the exact opposite. Losing implosion, creeper, egg and the almost certain nerf to juggler is going to make that deck a lot worse in standard IMO.
"A" variant of zoo will always persist, imo. It's the easiest hero power to abuse with valuable cheap minions and a general buff strategy. Losing creeper and egg, 2 super sticky value minions, is a blow, as is the tempo swing of an implosion especially paired with juggler, but I'd be shocked if, as a deck, it goes away.
That said I agree with D104, it certainly seems weakened to me.
I know it still shows up a bit, but I could see it becoming more prevalent.
- no more shredder to poop all over it, hard to think of any card that's more dominated by shredder than the drake
- we're losing three of the more popular 5-drops and something's going to have to fill the gap
- has that Loatheb thing of very rarely being a bad play
This is my prediction for future (and present) standard:
Keeper of the grove is the reason why Druid is OP, combo is a bit OP and needs a nerf (the 14 dmg thing is ok, the fact that any creature on board makes it 20 is the broken thing in that combo), but what makes druid so strong is that it's the only class that has a double silence included on a good card
I think they should make it 3/4 for 4 mana that deals 2 as battlecry and can't silence