As a former Small-Stakes-DON-Player I had to adjust my strategy on these and I have not finished yet but here is what I currently do:
Phase 1 (until Blinds 50/100): Goal is to survive or "easy" double up!
Basically same ultratight style as in DONs: Only AA, KK, sometimes QQ, and a little setmining now and then.
But in difference to DONs I also play AK and AQ!! from time to time because at the moment there are so many newbies in the Fifty50 $5.24 playing their weak aces or whatever they think is good enough that they are easy to exploit postflop. But I only do that against total newbies or proven bad players!
Phase 2 (until Blinds 150/300 or until less than 7 players):
Compared to DONs this is a crazy but still crucial phase in Fifty50s and I still don't know exactly how to handle it. I try to steal the blinds from time to time and use ICM pushes to build a stack > 3000.
Generally speaking pushing a bit wider than in DONs and even calling a bit looser.
If I have less than 1000 chips at the end of this phase I am looking for and accept any coinflip situations preflop, i.e. I even call with QJo if i think i'm up against a small pair.
Phase 3 (on the Bubble or Blinds >= 150/300):
I use two different approaches depending on my stack size:
a) As a small or average stack (<3000) i use the "old" surviving strategy like in DONs. Try to keep myself out of everything unless I have to act.
b) As mid or big stack (>3000) I loose up and bully the mid and small stacks to maximize my winnings. I achieve that by either using correct ICM pushes and calls or aggressive postflop play, i.e. quite the opposite of "normal" DON strategy.
I am sure this strategy has a lot of flaws and is far from being perfect but so far it works at least on $5.24 Fifty50 (ROI 6% in 1500 games).
Sometimes its hard for me to stick to either 3a or 3b strategy when multitabling since they differ so much.
My sample size for $10.48-Level isnt big enough (less than 500) to say anything. But it seems that I need to adjust this strategy for this level because i cant beat the rake here
Sorry for my bad english...but I hope it contributed at least something to the topic of this thread.