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I read somewhere that standardizing you betsizes on the first streets is the way to go
Yep, depends on villain. If villain is incompetent, you can do all sorts of wacky stuff. Vs. a good player though, unless you're ready to play the rock-paper-scissor game and can balance all of your ranges, a good way to not get soulread is to standardize your preflop raise size and continuation bet size. This means you make them independent of hand-strength, NOT independent of board texture. On dry boards that no one hits, like Q74r, a smaller 1/2 pot to 2/3 pot cbet suffices. On boards like QT9 with a 2-flush, you might want to raise 2/3 to 3/4 or even full pot. The idea behind this is that on the "wet" boards, each player's respective range is stronger, so in order to force errors in pot equity, betsizes much be larger. On the other hand, on dry boards, respective ranges are weaker, so a small bet is all that is necessary.
For HUCash, most people raise the pot, which is to 3BB. Then they fire 4BB as a standard into 6BB, but some people advocate betting 5BB as a standard.