Overall, it mostly depends on your opponents. 5+ years ago, I would guess that setmining made up a huge percentage of my winnings, because my opponents were mostly idiots who put in far too much money postflop with lol holdings. Today, most (but not all) tables I play at this has changed; my opponents are still super loose preflop like they've always been, but they are not postflop idiots (they know what is going on).
In this case here, if the limpers are loose passive idiots, then I think an argument could be made for flatting. We have position on the field (making getting paid off postflop easier), although we are to the direct left of the preflop raiser (not the best spot). If the limpers are all loose passive idiots, then good chance they'll come along for the preflop raise getting us 3:1 preflop (or 4+:1 if any of the Button/SB/BB come along), so we only have to make up a ~PSB postflop to breakeven, and if they are all idiots there is a decent chance we do that. However, if there is an ok chance someone was limping to reraise, or they are tight and will fold to the preflop raise, or they also have speculative hands and will only continue postflop if they hit well, then it's most likely a fold.
I would typically fold this in my game now.
ETA: Also, what squid said.
GeverythingisopponentdependentG