utg opens to 16 (straddle pot), utg+2 flats 16, I have AKo in CO, I 3b to 55, utg folds, utg+2 4b jams for ~350 total, I cover.

what should I be doing here? definitely conflicting signals here imo because aces are the #1 big hand that some people might just flatcall with pre, but you also would never expect someone to just straight up jam aces that deep rather than make a normal 4b. you also wouldn't really expect someone to limp kings, but you might expect them to jam them as a 4b. i'm 70% sure i'm flipping against exactly QQ/JJ because of course i block both of those hands but usually when someone in 1/2 jams preflop that deep it's AA or KK. i threw it away, would've happily called if this was less deep like maybe he's got ~200 total but that was a pretty deep jam. this is a correct fold, right?

Let me get this right.
1. If UTG opens for $16 it means you guys all called his straddle of $4 before the action got back to him for his option to raise?
2. Or the straddle was on the button (OTB) and in that case UTG acted as the 1st one in and pop it up to $16?

Now, that you 3bet to $55 after the utg+2 flats first the $16 and now he's coming over the top of you with $350. This may be the classic AA limp in EP hopping for a raise from LP and coming over the top when the action comes around the back to him. - Is he capable of setting up such a scheme?

Is he an infrequent raiser that sometime limps and sometimes raises?
In other words, by separating raising hands from limping hands, your opponent is giving you reliable info about when to back off. If that's the case,.. wtf? ...,You fold... man.. You fold!.., In any other case I still think is a fold unless you can be sure he's bluffing. You ask yourself this: Is he capable to make this play with AQ or less? - If the answer is No, ..You fold!

I mean, if I raise with AK and I get reraised with a "second hand low" play (this is what we got here. Are you aware of that?), I put some question to myself but I'm very very inclined to believe the reraise is legitimate, I don’t even think about it. When I say I don’t think about it, I mean seriously I don’t even think if I’m throwing a good hand away. I just put it right in the muck, like this,..., You see? That’s how fast I put it in there. You have to be 100% sure the 4! is a bluff or a weak hand before you touch that call.

The action needs cleaned up here. Do you mean the position after the straddle opened? Normal terminology is that the straddle is still UTG.

In any case though a flat/jam deep at 1/2 can be taken as AA/KK until you have seen villain do it lighter. This is a good situation for villain to turn up with a weaker hand but at 1/2 until you are sure villain is aggressive/bluffy or spazzy enough to shove lighter just fold.

I would just call with AK in position multiway myself. Especially if it's a 10 handed table. 4x open and a call in straddle pot, weird things happen in these spots.

First, 350 is not that deep. you are only calling 295, or 150 BB, to win ~ 720. so you are getting roughly 1.45 on your money. 600 is deep.

Most importantly, how does V view you? Do you have a big stack and have been pushing around the table? Have you been showing weakness and just calling alot?

I am more inclined to make this call if V has been splashing around in lots of pots and looking for lucky turn and river cards.

I would probably fold if V has been relatively inactive and this is the first big pot that he has played in the last 1 or 2 hours.

no