Yeah, calling pre is a very big mistake.
Against main V, there's only 3x the bet back, not even nearly enough to play a speculative hand OOP. There's also a chance that SB or OR jam. Even though that's a very small chance, it still takes away some equity.
You're about 16% to hit 2P+ or a combo flush draw. Even if you won every time one of those happened, you'd be right around breakeven. But obviously you're not winning even nearly 100% of the time.
OTF, you're actually a big favorite over V's KK+ (about 64% equity). Jamming is clearly correct.
While you're developing your preflop hand selection skills and getting a better understanding of how big the implied odds have to be for various types of hands (SCs, S1Gs, suited aces, PP), I'd suggest playing really tight and just folding them all. As you get teh mad skillz, you can add them in. But until then, mistakes cost far more than the value of the successes.
Generally, to play a speculative hand OOP, we're looking for two things:
- Lots and lots of money behind so that we can get paid when we hit it big.
- Good reads on our opponents so that we know when we can play aggressively and maybe steal, how to manipulate them so that they pay us off, and when we're beat even if we hit so that we can avoid a huge loss.
- Closing the action so that we don't invest and then have to dump the hand when someone else reopens things.
I've seen various rules of thumb: Something like 15x for PP, something like 20 - 25x for SCs, and something like 30+x for S1Gs and suited aces. But those numbers will go up and down depending on the specifics of the situation (e.g. IP vs. OOP, better or worse opponents, opponent predictability, relative position in a multi-way pot, HU vs. multi-way)