Probably folding river... You have too many queens in your range to expect this to be a bluff often. Pre is fine. Probably raising flop. Turn looks fine, but perhaps larger than it needs to be.
Seems like AQ or AQ. Hard for him to have a bluff here besides AT but you have Qx in your range so that's not the greatest bluff combo (though he blocks some of your Qx).
he doesnt have a lot of bluffs and you block some Kx combos that you're ahead of tho I dont know if he would try to VB them on this run out.
You also block a bunch of XclubXclub so its less likely he has missed clubs as well.
I think its going to come down to how light villain likes to bet rivers, the frequency with which villain will fire at boards that become scarier as hands progress, and then just how polarized villain will bet (ie. will even turn PP into bluffs etc etc) - and I guess just any sense of villains VB sizing, does he adjust this much - does he like to make big bets in spots where he will be more polarized etc.
Youre 300 BB deep even with the straddle so that 50 raise isnt super range defining PF either.
AP: I think this deep raising flop is super standard - you want to build that pot. On the turn you go from being able to improve to a Khi flush to being able to improve to a FH. Maybe a bigger bet on turn isnt terrible either.