This will work some of the time. It will get picked off enough that it is generally bad. The occasional two pair+ by villain or villain who actually reads your bluff are not the problem. With no read on villain, you will run into stations or villains who put everybody on AK too often. This will result in getting picked off with garbage single pairs too often for this to be profitable long term.
First, what are you doing playing NLHE instead of PLO?
Second, this is TOTALLY read-dependent. I'd say it's probably 70% given what I assume is the makeup of your table that you should expect a call, making this a -EV river play.
