"No colours appear on the vpip or pfr colums until players have 100 hands. Is there any way of changing this number to 50, or 75?"
Yes. Go to "main"->"options"->"profile".
There you can set the minimum number of hands for what the numbers count as valid. This minimum number of hands threshold has been added to avoid the distortion by players where you have e.g. only 15 hands.
This is also important for the "#Reads" column.
The first digit shows the number of players you have "enough" hands on (regarding to "main"->"options"->"profile"). The second digit shows how many player you have any hands from.
E.g. "4/6" means there are 4 players with at least "100" hands and 6 players with at least "0" hands.
The "#Loser" column just tells you how many players "Total Won" statistic is below zero at this table.
"In the middle screen, often the seat numbers are repeated, with some missing. Also, i do not show up when i am sitting."
At which pokerroom does this happen?
Also, a stars version, named Telescope, is already available:
http://www.spadeit.com/tindex.php
But datamining will never be added to this application because PokerStars does not allow this and i will not break their rules as i do not want that Telescope get on the PokerStars prohibited list.