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Even with tight 15% range vs 15% range at a single board, we have soooo many combos to mix with frequencies from 0.2 to 0.8. Is it really doable for humans ?
It isn't. Fortunately exact strategies doesn't matter that much. What counts is range composition (how many value bets, bluffs, which combos bet more often than others etc.). EV of plays matters as well (it's important not ot make blunders, less important to mix exactly as GTO is). The reason it's more important to focus on general range composition and EVs is that there are many strategies which are very close to GTO with different kind of mixing.
My view is that the following are useful when analyzing the solution:
1)Look at the range composition (Range Explorer is useful for that) determine how many very strong hands there are, how many pure bluffs, how many semibluffs. Compare betting range to checking range.
2)Look how the solver defends against common bluff lines. For example if you check behind the flop and the opponent bets both turn and river, how do you ensure you are not folding too much there, what are the calling hands the solver carries?
3)Consider the raising range composition, what are the hands there besides the nuts which are useful to have?
4)Check what plays are blunders, that is especially important against a bet as it's important not to fold too much.
5)On later streets try to find and get intuition for what is a good value bet (how strong the hand needs to be) and how tight you need to defend. Once you have good intuition about that you can make adjustments based on reads but it's very hard to make adjustmetns if you don't know what the neutral GTO play is in the first place
There are many other things you things and patterns you may try to find in the solutions. Learning frequencies by heart just won't work though. That's not Pio's fault either, it's just how optimal play is, there is a lot of mixing, especially on early streets when not facing a bet.