I dont think bluff is that profitable, we block a lot of other draws (that fold) and don't have many 86xx from ep. 63 not likely either and also discounted for sometimes checking turn. Similarly sets can often check one street on this texture.
So i think villain can (and should) call a lot of his better 2p+ combos, but we may fold some of his 1p that are also drawing and weaker 2p.
Not sure what sizing is optimal here when hero does bet, perhaps 30-35% psb.
I certainly don't think river bet is printing money at any size.
also folding that holding in EP pre. The Khi suit oop is bad and you're sacrificing with that monster gap. In full ring games the Ace hi suit is rarely folding so it's a legitimate concern. really the only flops you are going to feel comfortable with contain both a 6 and a 5. If i'm playing this hand i'm playing in late, getting in cheap multiway or isolating someone nitty.
As played (I like both streets and your sizing) I would barrel river, sizing down (around 50-60% pot) because draws miss and you want to appear as tho going for value. Ace is a good card for your range and may allow villain to abandon garbage two pair. If he shows up with AJxx oh well. I think the mostly likely holding that's going to snap you off is aces up, which is very concerning imo as he probably has ace hi flush draw + pair. This is enough to sway me to check and give up however you have zero showdown value, and betting is your only way to win. If you bet you're hoping he puts you on JJ, AA, AJ, maybe 86 or some set. I think you have enough fold equity to pull the trigger.