There's a lot of wishy-washy nonsense going on here.
I asked you to explain the difference between strategy and math:
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basically were all poker players here. you play 1 hand differently if you have 1 hand to play then if you have 10k hands with the same player. Me personally I would tag this down to strategy since its used that way in english, but if you were to say he did the math in his head and came out with that particular answer then w/e.
A GTO strategy plays the same way regardless of whether you play one or one thousand hands against some player. You can talk about dynamic strategies that are designed to exploit mistakes and adjust on the fly; but then you're no longer talking about GTO.
Any strategy can be represented mathematically, regardless of whether that strategy is dynamic or static.
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As far as GTO goes, you can't exploit true GTO because then it wouldn't be GTO in the first place, by definition. You can maybe exploit inaccuracies or limitations of the solution, with absolute GOD level play and an infinitely complex strategy. Similarly, you can beat a chess engine with GOD level play. But this is well outside the mortal realm.
A braindead push/fold strategy will lose horrifically in the long term.
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Let's design a HU strategy. You tell me the effective stack depth, and I'll solve the call/fold against that push. We lock that call/fold in, and then you can try to find a push/fold range that increases your EV.