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I read somewhere that if we 2bet and are facing a 3bet from a range with some 'bluffs' in it, we should continue in a way that makes his worst bluff 0EV. However this implies that we still allow all of his other bluffs that are just above his worst bluff to be +EV against us.
The idea that you want to make villain's worst bluffs 0EV is a toy game concept. It applies when villain is perfectly polarized to the absolute nuts and air with NO equity.
Preflop "bluffs" have equity, and preflop "value hands" aren't unbeatable. There are multiple players and multiple streets of betting. Some hands will over-realize equity, some will under-realize. So this toy game concept doesn't work well here.
Here's an example how how you would correct apply this:
Villain shoves river with the absolute nuts or complete air. You defend just enough to make their air indifferent to bluffing. If you defend less, they could bluff any two. If you defend more, they can stop bluffing and print with their value.
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Why are we not trying to make some of his worst bluffs -EV for him so that in the future he reconsiders doing them against us
Because then they could stop bluffing and exploit you.
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Where is our profit coming from with our continuing range if it only breaks even against our opponent's worst hand?
Their bluffs are break-even against our range (when considering fold equity). Our continue range is not breaking even against their bluffs.