Originally Posted by skater3598
Wear the brace when you sleep. I'm a long time computer gamer so my clicking actions are extremely intense and I transferred that to poker
Funny fact I learned while researching carpal tunnel: your wrist is twisted 90º from the elbow when it's faced palm down, and even and straight when your palm is facing the horizon
This is exactly right, the position of holding a mouse and typing twists the muscles and tendons in our hands really badly. The natural position is instead with your thumbs facing up, which would lend itself to an upright mouse. I found however, the upright mouse still requires you to grip the mouse too much. A trackball makes a huge difference because you don't have to grip the mouse and you can get your hand at a better angle. Also try a natural keyboard rather than a traditional keyboard. You can beat the pain by changing your habits, but its takes an incredible amount of patience and self discipline to change our habits so drastically.
See the section called "Other Recommended Equipment" here for some other products/techniques I've found that help tremendously.