vs. min-raise, defending a lot of hands (80-90%?) since you are getting a great price.
vs. a 3x raise, still a lot of hands but subtract some if the player give you more trouble post-flop
as far as 3betting, it's up to you.
lefort made a great series that included a lot of good ideas about this topic, particular this one in general (I think this is the one where he talks about 'R'):
http://www.runitonce.com/pro-training/videos/lefort2/