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What were some of the sickest burns you've dished out to people in conversation? It could be with friends, enemies, strangers, co-workers, weirdos at a club trying to pick up your girlfriend, whatever.
The best one I remember was about six years ago to a very macho and homophobic friend of mine at a party. The subject turned to men's health and testicular cancer. He was saying how checking your own balls on a regular basis is very important in addition to getting your physical.
Being the sick minded ****er that I am, I asked him, "have you ever looked down and saw four testicles?" Everybody erupts in laughter. I don't think I've ever seen him that embarrassed and angry. LOL