Quote:
Originally Posted by winnercircle
Gangstaman, regarding prescription drugs: they only have to beat a placebo in one test right? Regardless of whether or not they've failed to beat a placebo in the previous 30.
Well, 2 trials, not 1. It's not much, but it's more than vitamins/supplements/other things which don't require any studies of any quality.
Quote:
Originally Posted by kcernest
There have been anthropological studies on indigenous tribes with no exposure to grains or high carb sources in their diets. None of these tribes have any instance of metabolic disease or arthritis.
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Sorry about not posting references, I'm just too lazy to look around and post links when everyone here should know how to work the Google machine.
I always advocate reading research papers over 'bro-science' but the problem is funding for research that could potentially hurt a multi billion dollar industry doesn't really exist. Nobody is out there writing checks to do research that doesn't lead to sales of a new product.
The issue is that while I know how to work google well, I wasn't impressed with what I read. There are animal studies that look good, and some data with Alzheimer's, but nothing good with 'normal' humans. So I was curious if you knew of studies that I didn't find.
Of course, there are certainly reasons that such studies typically don't exist. I'm not as cynical as you to think that the issue is that a successful study with the ketogenic diet would hurt the pharma industry, but I do agree that since no one can really make money off it no one's willing to put up the money to fund studies. So we're left with studies that are a step removed from what we actually want to know (like I reference above), or studies like you mention here that have too many possible confounding factors to know what to make of them.
I'm a child/adolescent psychiatrist, so I'm actually quite used to recommending treatments with a poor evidence base. There are times when you don't have much choice because the evidence simply doesn't exist. But I try to be honest about it, at least, and try to avoid putting down other treatment options that are as supported in the literature.
Quote:
Originally Posted by kcernest
The thing about drugs is they are meant to deal with a symptom, not a cause.
I don't know that we can say supplements or diets are really any different. For many things, we don't quite know the cause so no treatment can really be designed to treat the cause. And for many other things, the cause just isn't treatable yet. I don't know that addressing symptoms is really all that bad when we don't know how to reverse the cause.