This should prolly be posted in MSMTT or HSMTT instead.
But bigger pre, it makes it easier to gii ott on gross boards if he flats. With no information on the table, I'm never folding QQ pre 45x deep to a single raise, meaning that I'm either flatting or 3betting with the intention of gii. I think at low stakes where the fields are really soft, you can make a decent argument for flatting in BB (you're closing the action) and playing the hand hu oop to pot control (although it's definitely not my default), but at these stakes with much tougher opponents, you just don't get enough hands to fold QQ hu on 45x without a read that justifies a fold. If he has it, it's just a cooler.