In the 19 game dealer's choice spread at WSOP, a number of top players said they tried to choose stud hi/lo regular as much as possible, for two stated reasons:
1) the instant a player plays a high card up, they instantly mark themselves as something of a mixed game fish
2) this is the game in which players can make the biggest mistakes, essentially freerolling themselves from 3rd street onward
I've never played. Seems like a very interesting game. I'd probably play pretty poorly