Hero has been quiet, but is now short after an unsuccessful barrelling expedition against this very Vil (see below). Makes a loose call from the bb with Q-3

's for $7 (MP made it the standard table raise). Players, stack sizes and profiles are as follows:
Hero (big blind) -$175 [Folded around in first 2-3 orbits; noticed that table plays mostly passive; small standard opening ($7), lots of limping; few raises postflop. Only involved hand happened an orbit ago, Vil #1 in this hand called hero's barrel down when Hero bet 6-7 sooted preflop, cbet when paired his 6 OTF, c/c on 4th and made a healthy bet OTR. Vil #1 snap-called him down with A-K (A on the flop).
Vil #1 (UTG +1) - $325 [Young dude with neat beard & ball cap; seems to react a little emotionally at the table. But seems to play reasonably; we haven't seen him out of line. Probably open-raises more than limps; seems positionally aware; but no head to head experience except the above hand.]
Vil #2 (MP) - $225 [Old fishy dude. Called a couple big preflop raises (set-mining, probably. Seen call off $30-50 a couple times and give up on river. =Will chase draws. ]
Vil #3 (LP) - $250 (not involved after flop)
To the flop we go, 4 ways (pot $28)
K

10

6

-- Checks through.
Turn: Q

(Pot: $28)
Hero leads $12, Vil #2 & #3 both smooth call. (Logic: Hero has picked up some real equity: second pair & the third-best flush draw. No one has shown an interest; time to build a pot in case hand improves).
River: 4

(Pot: $64)
Hero leads $25, Vil #1 raises to $60, Vil #2 folds. (Pot: $159)
$35 to go for Hero, who has committed 25% of his stack & now has ~ $130 remaining).
Range question (reason for thread): Hero, not normally this nitty, is thinking about the concept of a "protected bet" as fishy Vil #2 shows up w/ a made Flush here pretty often.
Hero only needs immediate odds of 22% to just call with third nuts. Best line ?