Originally Posted by Slide
Honestly this seems totally backwards to me. I think a much better solution is to error on the side of getting to showdown and seeing what they have rather than assume their bets make sense and they play logical. If we're wrong we lose 1-2 BBs, if we're right we would have made a much bigger mistake by folding.
You won't be right often enough to pay for the 1-2 BBs you will lose the vast majority of the time.
This has been one of the harder (but more important) adjustments I've made to my 6-12 play -- learning to know when to let the damned hand go. When I first started playing, I thought exactly like what you just said. After paying those 1-2 BBs over and over, I finally learned to start paying attention to when people donk or raise me after I've been doing all the betting/raising.
Now, when I've been betting the whole hand, and someone donks or raises me, it's a snap fold 95% of the time, unless I've got the outs to call, or it's on the river and the pot is ginormous.
[Adding: I don't play much outside of the one club I play at. Maybe 6-12 players elsewhere are different, but where I play, the above holds true.]