If the guy is literally not going to fold or call way to wide then shoving hands that dont beat ATC could be costing you money although your range as a whole will do fine.
Are there other reasons for shoving tighter than nash?
If we have a pretty noticeable edge over the rest of the table then we can adjust our jamming range and take out certain hands. The EV we expect to gain from the rest of the table vs our relative edge should out weigh the lost EV that the player gets from us tightening our jamming range and the EV of the Jam itself.
Aren't we referring to a profitable heads up strategy? So rest of table shouldn't matter.
